CURRICULUM VITAE 

Jan A. Smalle

Assistant Professor
Department of Plant and Soil Sciences

professional preparation

Undergraduate: Ghent University ( Belgium) Plant Biotechnology     B.S. 1987

Graduate: Ghent University ( Belgium) Plant Genetics     Ph.D. 1998

Postdoctoral: University of Wisconsin ( Madison) Ubiquitin-dependent proteolysis 1998-2004

appointments

2004:   Assistant Professor, Department of Plant and Soil Sciences, University of Kentucky, Lexington, KY.

1998–2004:   Research Associate, Laboratory of Genetics, University of Wisconsin-Madison, Madison, WI.

1991–1998:   Research Assistant, Laboratory of Genetics, Ghent University, Ghent, Belgium.

1989–1991:   Visiting Fellow, Department of Molecular Biology, Harvard University, Boston, MA.

1988–1989:   Research Assistant, Laboratory of Genetics, Ghent University, Ghent, Belgium.

publications

Refereed

• De Paepe, L. De Grauwe, S. Bertrand, J. Smalle and D. Van Der Straeten (2005). The Arabidopsis mutant eer2 has enhanced ethylene responses in the light. Journal of Experimental Botany, in press.

• J. M. Gagne, J. Smalle, D. Gingrich, J.M. Walker, S. Yoo, S. Yanagisawa and R. D. Vierstra (2004). The Arabidopsis F-box proteins EBF1 and 2 form SCF E3s that repress ethylene action and promote growth by directing EIN3 degradation. Proceedings of the National Academy of Sciences of the USA101, 6803-6808.

• P. Yang, H. Fu, J. Walker, C.M. Papa, J. Smalle, Y. Ju and R.D. Vierstra (2004). Purification of the Arabidopsis 26S proteasome: biochemical and molecular analyses revealed the presence of multiple isoforms. Journal of Biological Chemistry279, 6401-6413.

• F. Vandenbussche, W. H. Vriezen, J. Smalle, L.J.J. Laarhoven, F.J.M. Harren and D. Van Der Straeten (2003). Ethylene and auxin control the Arabidopsis response to decreased light intensity. Plant Physiology 133, 517-527.

• J. Smalle, J. Kurepa, P. Yang, T. Emborg, E. Babiychuk, S. Kushnir and R. D. Vierstra (2003). The pleiotropic role of the 26S proteasome subunit RPN10 in Arabidopsis thaliana growth and development supports a substrate-specific function in abscisic acid signaling. The Plant Cell 15, 965-980.

• J. Kurepa, J. M. Walker, J. Smalle, M. M. Gosink, S. J. Davis, T. L. Durham, D. Sung and R. D. Vierstra (2003). The sumo protein modification system in Arabidopsis: accumulation of sumo1 and sumo2 conjugates is increased by stress. Journal of Biological Chemistry 278, 6862-6872.

• F. Vandenbusche, J. Smalle, J. Le, N. Jose Madiera Saibo, A. De Paepe, L. Chaerle, O. Tietz, R. Smets, L. J. J. Laarhoven. F. J. M. Harren, H. Van Onckelen, K. Palme, J. Verbelen and D. Van Der Straeten (2003). The Arabidopsis thaliana mutant alh1 illustrates a cross-talk between ethylene and auxin. Plant Physiology 131, 1228-1238.

• J. Smalle, J. Kurepa, P. Yang, E. Babiychuk, S. Kushnir, A. Durski and R. D. Vierstra (2002). Cytokinin growth responses in Arabidopsis thaliana involve the 26S proteasome subunit RPN12. The Plant Cell14, 17-32.

• J. Smalle, M. Haegman, J. Mertens, J. Vangronsveld, M. Van Montagu and D. Van Der Straeten (1999). The expression pattern of the Arabidopsis ACC synthase gene 1 during rosette development. Journal of Experimental Botany 50, 1561-1566.

• J. Smalle, J. Kurepa, M. Haegman, J. Gielen, M. Van Montagu and D. Van Der Straeten (1998). The trihelix-binding motif in higher plants is not restricted to the transcription factors GT‑1 and GT‑2. Proceedings of the National Academy of Sciences of the USA95, 3318‑3322.

• J. Kurepa, J. Smalle, M. Van Montagu and D. Inzé (1998). Effects of sucrose supply on growth and paraquat tolerance of the late‑flowering gi‑3 mutant. Plant Growth Regulation 26, 91‑96.

• J. Kurepa, J. Smalle, M. Van Montagu and D. Inzé (1998). Polyamines and paraquat toxicity in Arabidopsis.Plant and Cell Physiology 39, 987‑992.

• J. Kurepa, J. Smalle, M. Van Montagu and D. Inzé (1998). Oxidative stress tolerance and longevity in Arabidopsis: the late‑flowering mutant gigantea is tolerant to paraquat. The Plant Journal 14, 759‑764.

• J. Smalle, M. Haegman, J. Kurepa, M. Van Montagu and D. Van Der Straeten (1997). Ethylene can stimulate Arabidopsis hypocotyl elongation in the light.Proceedings of the National Academy of Sciences of the USA 94, 2756‑5761.

• D. A. Wright, N. Ke, J. Smalle, B. Hauge, H. M. Goodman and D. F. Voytas (1996). Multiple non-LTR retrotransposons in the genome of Arabidopsis thaliana. Genetics 142, 569-578.

• C. Valon, J. Smalle, H. M. Goodman and J. Giraudat (1993). Characterization of an Arabidopsis thaliana gene (TMKL1) encoding a putative transmembrane protein with an unusual kinase-like domain. Plant Molecular Biology 23, 415-421.

• D. Van Der Straeten, A. Djudzman, W. Van Caeneghem, J. Smalle and M. Van Montagu(1993). Genetic and physiological analysis of a new locus in Arabidopsis that confers resistance to 1-aminocyclopropane-1-carboxylic acid and ethylene and specifically affects the ethylene signal transduction pathway. Plant Physiology 102, 401-408.

• J. Giraudat, B. M. Hauge, C. Valon, J. Smalle, F. Parcy and H. M. Goodman (1992). Isolation of the Arabidopsis ABI3 gene by positional cloning. The Plant Cell 4, 1251-1261.

• B. Claes, J. Smalle, R. Dekeyser, M. Van Montagu and A. Caplan (1991). Organ-dependent regulation of a plant promoter isolated from rice by promoter-trapping in tobacco. Plant Journal1, 15-26.

Reviews and Book Chapters  

• J. Smalle and R. D. Vierstra (2004). The ubiquitin/26S proteasome proteolytic pathway. Annual Review of Plant Biology 55, 555-590.

• D. Van Der Straeten, J. Smalle and M. Van Montagu (1999). Ethylene. In: Encyclopedia of Molecular Biology, T.E. Creighton (Ed.). New York, Wiley & Sons.

• J. Smalle and D. Van Der Straeten (1997). Ethylene and vegetative development. Physiologia Plantarum 100, 593-605.