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David L. Harmon, Ph. D.

Professor, Beef Coordinator.  Ruminant Nutrition;  Digestive Physiology
Director of Graduate Studies
Department of Animal Sciences
University of Kentucky
814 W.P. Garrigus Bldg
Lexington, KY 40546
Telephone:  (859) 257-7516
FAX:  (859) 257-3412
E-mail:  dharmon@uky.edu


EDUCATION

Ph.D., University of Nebraska-Lincoln
Major: Animal Science (Ruminant Nutrition); 1980-1983
Dissertation topic: D(-) lactate metabolism in beef cattle
Major advisor: Dr. R. A. Britton

M.S., University of Nebraska-Lincoln
Major: Animal Science (Ruminant Nutrition); 1978-1980
Thesis topic: Acidosis, lactate and mineral metabolism associated with high concentrate feeding
Major advisor: Dr. R. A. Britton

B.S., The Ohio State University
Major: Nutrition, 1974-1978


EXPERIENCE

Department of Animal Science and Industry, Kansas State University
August 1983 -February 1989, Assistant Professor
Appointment .6 Research - .4 Teaching

February 1989 - December 1991, Associate Professor
Department of Animal Sciences, University of Kentucky

January 1992 - present, Associate Professor
Appointment .75 research - .25 Teaching
July 1995 - present, Professor


Teaching

Laboratory Methods in the Nutritional Sciences, Graduate lecture and laboratory. Advanced Ruminant Nutrition, Graduate lecture. Experience with graduate and undergraduate courses.

      - Fundamentals of Nutrition, Introductory undergraduate nutrition.
    ..  - Animal Nutrition, Graduate, nutritional physiology and metabolism.
    ..  - Analytical Techniques in Animal Science, Graduate laboratory methods.
    ...- Radioisotopes and Radioimmunoassay, Graduate laboratory methods.
    ...- Techniques in Animal Nutrition Research, Graduate lecture and laboratory.
    ...- Advanced Ruminant Nutrition, Graduate lecture.


Additional Activities

IACUC College of Agriculture Subcommittee Chair (1997-present) Chair, Director of Graduate Studies (2002-Present)


Research

Research program has dealt with identifying relationships between diet digestion, gut metabolism and nutrient absorption in ruminants. The major objectives are:

Proficiency in a variety of surgical techniques for nutrition studies.

    - Ruminal, duodenal, ileal and esophageal cannulations.
    - Hepatic, portal and arterial catheterizations.
    - - cannulation. Experience with in vivo and in vitro use of metabolic tracers.
    - Use of tissues for in vitro metabolic studies.
    - In vivo measurement of nutrient flux and absorption. Proficient with most laboratory equipment and analyses.

Additional Activities

Member of University Animal Care Use and Committee (KSU and UK) IACUC College of Agriculture Subcommittee Chair (1997-present) Chair, Beef commodity group UK (1993-present)


AFFILIATIONS AND HONORS

American Society of Animal Science Director at Large 1999-2002

American Society of Animal Science AFIA Ruminant Nutrition Award- 1998

Journal of Animal Science-Section Editor Ruminant Digestion and Metabolism - 1992-1995

Midwest American Society of Animal Science Young Researcher Award - 1992  

American Institute of Nutrition

American Society of Animal Science

Gamma Sigma Delta

Sigma Xi

Widaman Trust Outstanding Graduate Student Award, 1982.


Recent Publications

Huntington, G.B., D.L. Harmon, and C.J. Richards. Sites, rates, and limits of starch digestion and glucose metabolism in growing cattle. Journal of Animal Science 84:E14-E24. 2006.

Huntington, G.B., D.L. Harmon, N.B. Kristensen, K.C. Hanson, and J.W. Spears. Effects of a slow-release urea source on absorption of ammonia and production of urea by cattle. Animal Feed Science and Technology 130:225-241. 2006.

Kitts, S.E., D.L. Harmon, E.S. Vanzant, and K.R. McLeod. Effects of chlortetracycline (CTC) and Revalor-S on the growth performance and carcass quality traits of finishing beef steers. Journal of Animal and Veterinary Advances 5: 70-76. 2006.

Mouro, G.F., A.F. Branco, D.L. Harmon, F.J. Maia, S.M. Coneglian, and T.F.M. Ribeiro. Fontes de carboidratos e ionoforo em dietas contendo oleo vegetal para ovinos: digestibilidade, balanco de nitrogenio e fluxo portal de nutrients. Revista Brasileira de Zootecnia 35: 2144-2153. 2006.

Yamka, R.M., D.L. Harmon, W.D. Schoenherr, C. Khoo, K.L. Gross, PhD; S.J. Davidson, and D.K. Joshi. In vivo measurement of flatulence and nutrient digestibility in dogs fed poultry by-product meal, conventional soybean meal, and low-oligosaccharide low-phytate soybean meal. American Journal of Veterinary Research 67:88-94. 2006.

Kristensen, N.B., G.B. Huntington and D.L. Harmon. Splanchnic carbohydrate and energy metabolism in growing ruminants. pp. 405-432. In: Biology of Growing Animals Series. Biology of Metabolism in Growing Animals. D.G. Burrin and H. J. Mersman (Eds.). Elsevier, Boston. 2005.

Yamka, R.M., U. Jamikorn, A.D. True and D.L. Harmon. Evaluation of low-ash poultry meal as a protein source in canine foods. Journal of Animal Science 81:2279-2284. 2003.

Yamka, R.M., U. Jamikorn, A.D. True and D.L. Harmon. Evaluation of soybean meal as a protein source in canine foods. Animal Feed Science Technology 109:121-132. 2003.

Swanson, K.C., J.C. Matthews, C.A. Woods and D.L. Harmon. Influence of substrate and/or neurohormonal mimic on in vitro pancreatic enzyme release from calves post-ruminally infused with partially hydrolyzed starch and/or casein. Journal of Animal Science 81:1323-1331. 2003.

Richards, C.J., K.C. Swanson, S.J. Lewis, D.L. Harmon and G.B. Huntington. Pancreatic exocrine secretion in steers infused post-ruminally with casein and cornstarch. Journal of Animal Science 81:1051-1056. 2003.

Swanson, K.C., J.C. Matthews, C.A. Woods, and D.L. Harmon. 2002. Post-ruminal administration of partially hydrolyzed starch and casein influences pancreatic α-amylase expression in calves. Journal of Nutrition 132:376-381.

Akay, V., J.A. Jackson Jr., and D.L. Harmon. 2002. NutriDense and waxy corn hybrids: Effects on site and extent of disappearance of nutrients in sheep. Journal of Animal Science 80:1335-1343.

Harmon, D.L., C.J. Richards, K.C. Swanson, J.A. Howell, J.C. Matthews, G.B. Huntington, A.D. True, S. Gahr, and R.W. Russell. 2001.  Influence of ruminal or postruminal starch on visceral glucose metabolism in steers. pp. 273-276. IN: A. Chwalibog and K. Jakobsen, eds. Energy Metabolism in Animals. Proceedings,15th International Symposium on Energy Metabolism, Snekkersten, Denmark. Wageningen Pers, Wageningen, the Netherlands.

Harmon, D.L., and K.R. McLeod. 2001. Glucose uptake and regulation by intestinal tissues: Implications and whole-body energetics. Jour-nal of Animal Science, 79:E59-E72.

Harmon, D.L., C.J. Richards, K.C. Swanson, J.A. Howell, J.C. Matthews, A.D. True, G.B. Huntington, S.A. Gahr, and R.W. Russell. 2001.  Influence of ruminal or postruminal starch on visceral glucose metabolism in steers. EAAP Publication No. 103. pp. 273- 276. Proceedings, 15th International Symposium on Energy Me-tabolism, Snekkersten, Denmark.

Howell, J.A., A.D. Matthews, K.C. Swanson, D.L. Harmon, and J.C. Matthews. 2001. Molecular Identification of high-affinity glutamate transporters in sheep and cattle forestomach, intestine, liver, kid-ney, and pancreas. Journal of Animal Science, 79:1329-1336.

McLeod, K.R., R.L. Baldwin VI, D.L. Harmon, C.J. Richards, and W.V. Rumpler. 2001. Influence of ruminal and postruminal starch infu-sion on energy balance in growing steers. EAAP Publication No. 103. pp. 217-220. Proceedings, 15th International Symposium on Energy Metabolism, Snekkersten, Denmark.

Bauer, M.L., D.L. Harmon, D.W. Bohnert, A.F. Branco, and G.B. Huntington. 2001. Influence of α-linked glucose on sodium-glucose cotransport activity along the small intestine in cattle. Journal of Animal Science, 79:1917-1924.

Swanson, K.C., J.C. Matthews, A.D. Wilson, J.A. Howell, C.J. Richards, and D.L. Harmon. 2000. Influence of dietary carbohydrate source and energy intake on pancreatic alpha amylase expression in lambs. J. Nutr. 130:2157-2165.

Swanson, K.C., D.L. Harmon, K.A. Jacques, B.T. Larson, C.J. Richards, D.W. Bohnert and S.J. Lewis. 2000. Efficacy of chromium yeast for growing beef steers. Anim. Feed Sci. Technol. 86:95-105.

Strickling, J. A., D.L. Harmon ,K.A. Dawson and K.L. Gross. 2000. Evaluation of oligosaccharide addition to dog diets: influences on nutrient digestion and microbial populations. Anim. Feed Sci. Technol. 86:205-219.

Silvio, J., D.L. Harmon, K. L. Gross, and K. R. McLeod. 2000. Influence of fiber fermentability on nutrient digestion in the dog. Nutrition. 16:289-295.

Ludden, P. A., D. L. Harmon, B. T. Larson and D. E. Axe. 2000. Influence of the novel urease inhibitor N-(n-butyl) thiophosphoric triamide (NBPT) on ruminant nitrogen metabolism. 1. In vitro urea kinetics and substrate digestion. J. Anim. Sci. 78:181-187.

Ludden, P. A., D. L. Harmon, G. B. Huntington, B. T. Larson,and D. E. Axe. 2000. Influence of the novel urease inhibitor N-(n-butyl) thiophosphoric triamide (NBPT) on ruminant nitrogen metabolism. 2. Ruminal nitrogen metabolism, diet digestibility, and nitrogen balance in lambs. J. Anim. Sci. 78:188-198.

Bohnert, D. W, D. L. Harmon , B. T. Larson, C. J. Richards, and M. N. Streeter. 2000. Efficacy of laidlomycin propionate in low-protein diets fed to growing beef steers: effects on steer performance and ruminal nitrogen metabolism. J. Anim. Sci. 78:173-180.

Bohnert, D.W., B.T. Larson, S.J. Lewis, C.J. Richards, K.C. Swanson, D.L. Harmon and G.E. Mitchell, Jr. 1999. Net nutrient flux by visceral tissues of lambs fed diets differing in supplemental nitrogen source. J. Anim. Sci. 77:2545-2553.

Branco, A.F., D.L. Harmon, D.W. Bohnert, B.T. Larson and M.L. Bauer. 1999. Estimating true digestibility of carbohydrate in the small intestine of steers. J. Anim. Sci. 77:1889-1895.

Larson, B.T., D.L. Harmon, L.P. Bush, E.L. Piper and L.M. Griffis. 1999. Alkaloid binding and activation of D2 dopamine receptors in cell culture. J. Anim. Sci. 77:942-947.

Harmon, D.L., J.A. Walker, J.M. Silvio, A.M. Jamikorn and K.L. Gross. 1999. Nutrient digestibility in dogs fed fiber-containing diets. Vet. Clin. Nutr. 6:6-10.

ABSTRACTS

Huntington, G.B., C. Richards and D. Harmon. Sites, rates and limits of carbohydrate digesiton and glucose metabolism in growing cattle. Journal of Animal Science 83:(Suppl. 1) 72. 2005.

Taylor, C.C., N.A. Elam, S.E. Kitts, K.R. McLeod, D.E. Axe and D.L. Harmon. Influence of slow-release urea on nitrogen balance and nutrient absorption of steers. Journal of Animal Science 83:(Suppl. 1) 321. 2005.

Speight, S.M. and D.L. Harmon. Application of carbohydrase inhibitors to moderate rumen fermentation: In vitro evaluation. Journal of Animal Science 83:(Suppl. 1) 307. 2005.

Huntington, G.B., C. Richards and D. Harmon. Sites, rates and limits of carbohydrate digesiton and glucose metabolism in growing cattle. Journal of Animal Science 83:(Suppl. 1) 72. 2005.

Elam, N.A., C. Taylor, S.E. Kitts, K.R. McLeod, D.L. Harmon and E.S. Vanzant. Quantitative assessment of visceral energy metabolism in beef steers consumed graded levels of forage. Journal of Animal Science 83:(Suppl. 1) 52. 2005.

Rodriguez, S.M., K.C. Guimaraes, J.C. Matthews, K.M. McLeod, R.L. Baldwin and D.L. Harmon. Influence of abomasal carbohydrate on small intestinal sodium-dependent glucose co-transporter activity in steers. Journal of Animal Science 81(Suppl. 1):266. 2003.

Yamka, R.M., K.R. McLeod. D.L. Harmon, H.C. Freetly and W.D. Schoenherr. Accounting for the proportion of alpha-amino nitrogen in crude protein improves metabolizable energy prediction in dry extruded dog foods. Journal of Animal Science 81(Suppl. 1):260. 2003.

Fisher, M.J., D.W. Bohnert, C.J. Ackerman, C.S. Schauer, T. DelCurto, A.M. Craig, E.S. Vanzant, D.L. Harmon and N.F. Schrick. Evaluation of perennial ryegrass straw as a forage source for ruminants. Journal of Animal Science 81(Suppl. 1):34. 2003.

Hanson, K.C., S.E. Kitts, N.B. Kristensen, D.E. Axe and D.L. Harmon. Effects of feeding a slow-release urea on ruminal nitrogen dynamics in steers. Journal of Animal Science 81(Suppl. 1):265. 2003.

Bohnert, D.W., C.S. Schauer, S.J. Falck and D.L. Harmon. Comparison of urea and soybean-meal as nitrogen supplements to cool-season, low-quality forage: I. Daily and alternate day supplementation effects on digestion and ruminal fermentation in steers. Journal of Animal Science 81(Suppl. 1):92. 2003.

Experiment Station Reports

Kristensen, N.B. and D.L. Harmon. Metabolism of volatile fatty acids absorbed from the washed rumen of steers. 2004 Beef Research Report. KY Agr. Report SR-2004-2. pp. 27. 2004.

Refereed Journal Articles

Bertram, H.C., N.B. Kristensen, A. Maldendal, N.C. Nielsen, R. Bro, H.J. Andersen and D.L. Harmon. A metabolomic investigation of splanchnic metabolism using 1H NMR spectroscopy of bovine plasma. Analytica Chimica Acta 536:1-6. 2005.

Other Refereed Journal Articles

Yamka, R.M., S.E. Kitts and D.L. Harmon. Evaluation of low-oligosaccharide low-phytate whole soybeans in canine foods. Animal Feed Science Technology 120:79-91. 2005.

Yamka, R.M., B.M. Hetzler and D.L. Harmon. Evaluation of low-oligosaccharide low-phytate whole soybeans and soybean meal in canine foods. Journal of Animal Science 83:393-399. 2005.

Kristensen, N.B. and D.L. Harmon. Effect of adding valerate, caproate, and heptanoate to ruminal buffers on splanchnic metabolism in steers under washed-rumen conditions. Journal of Animal Science 83:1899-1907. 2005.

Bertram, H.C., N.B. Kristensen, A. Maldendal, N.C. Nielsen, R. Bro, H.J. Andersen and D.L. Harmon. A metabolomic investigation of splanchnic metabolism using 1H NMR spectroscopy of bovine plasma. Analytica Chimica Acta 536:1-6. 2005.

Swanson, K.C., J.A. Benson, J.C. Matthews, and D.L. Harmon. Pancreatic exocrine secretion and plasma concentration of some gastrointestinal hormones in response to abomasal infusion of starch hydrolysate and/or casein. Journal of Animal Science 82:1781-1787. 2004.

Benson, J.A., K.C. Swanson, J.C. Matthews, and D.L. Harmon. Influence of Starch Hydrolysate and/or Casein on Pancreatic Exocrine Secretion and Plasma Hormone Concentrations in Beef Steers. Journal of Animal Science 82:1781-1787. 2004.

Bertram, N.B. Kristensen, A. Malmendal, N.C. Nielsen, S. K. Jemsern, and D.L. Harmon. Use of NMR-based metabolomics to assess metabolism in splanchnic tissues of steers. Journal of Animal Feed Science 13: (Suppl. 1) 295-298. 2004.

Fisher, M.J., D.W. Bohnert, C.J. Ackerman, C.S. Schauer, T. DelCurto, A.M. Craig, E.S. Vanzant, D.L. Harmon, and N.F. Schrick. Evaluation of perennial ryegrass straw as a forage source for ruminants. Journal of Animal Science 82:2175-2184. 2004.

Harmon, D.L., R.M. Yamka, and N. Elam. Factors affecting intestinal starch digestion in cattle. Can. Journal of Animal Science 84:309-318. 2004.

Kristensen, N.B. and D.L. Harmon. Splanchnic metabolism of VFA absorbed from the washed reticulorumen of steers. Journal of Animal Science 82:2033-2042. 2004.

Kristensen, N.B. and D.L. Harmon. Effect of increasing ruminal butyrate absorption on splanchnic metabolism of VFA absorbed from the washed reticulorumen of steers. Journal of Animal Science 82:3549-3559. 2004.

Raun, B.M.L., N.B. Kristensen, and D.L. Harmon. Splanchnic metabolism of propylene infused into the jugular vein of steers under washed rumen conditions. Journal of Animal Feed Science 13: (Suppl. 1) 331-334. 2004.

Rodriguez, S.M., K.C. Guimaraes, J.C. Matthews, K.R. McLeod, R.L. Baldwin VI, and D.L. Harmon. Influence of abomasal carbohydrates on small intestinal sodium-dependent glucose co-transporter activity and abundance in steers. Journal of Animal Science 82:3015-3023. 2004.

Yamka, R.M., S.E. Kitts, A.D. True, and D.L. Harmon. Evaluation of corn gluten meal as a protein source in canine foods. Animal Feed Science Technology 116:239-248. 2004.

Experiment Station Reports & Bulletins

Hanson, K.C., K.R. McLeod, and D.L. Harmon. Effect of supplemental energy source on performance of growing beef heifers fed drought-damaged corn silage. 2004 Beef Research Report. KY Agr. Report SR-2004-2. pp. 8. 2004.

Hanson, K.C., K.R. McLeod, J. Tricarico, and D.L. Harmon. Effect of exogenous amylase and corn type on performance and characteristics of finishing beef heifers. 2004 Beef Research Report. KY Agr. Report SR-2004-2. pp. 22. 2004.

Hanson, K.C., S.E. Kitts, D.L. Harmon, and D.E. Axe. Influence of Bufferfos®on the ruminal environment of steers fed high-grin diets. 2004 Beef Research Report. KY Agr. Report SR-2004-2. pp. 25. 2004.

Harmon, D.L., K.C. Hanson, S.E. Kitts, N.B. Kristensen, K.R. McLeod, and D.E. Axe. Influence of slow-release urea on digestion and metabolism of ruminants. 2004 Beef Research Report. KY Agr. Report SR-2004-2. pp. 29. 2004.

Kitts, S.E., K.C. Hanson, N.A. Elam, M.C. Newman, D.L. Harmon, and K.R. McLeod. Effects of corn type and forage level on growth performance and E.Coli shedding in finishing beef steers. 2004 Beef Research Report. KY Agr. Report SR-2004-2. pp. 9. 2004.

Kristensen, N.B. and D.L. Harmon. Metabolism of volatile fatty acids absorbed from the washed rumen of steers. 2004 Beef Research Report. KY Agr. Report SR-2004-2. pp. 27. 2004.

 
 

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