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National Animal Genome Research Program Species Coordinator for the Horse
E. Bailey
Department of Veterinary Sciences
Project Description
Meetings were supported at the Plant and Animal Genome Conference in San Diego in January 2007 and at the Havemeyer Horse Genome Conference at Lake Tahoe in August 2007. Travel for scientists and their students working in connection with horse genomics was supported for these meetings. Work was supported to assist the Broad Institute or at MIT/Harvard in the assembly of the horse genome. The first assembly was reported, online, in February 2007 and the second is in progress. In addition, work was supported to develop genome research tools in connection with a research project funded by the Morris Animal Foundation (equine medical genetics). The website for the workshop (http://www.uky.edu/Ag/Horsemap) was redesigned to promote the use of the newly developed horse genome sequence and associated tools. The coordinator also made presentations to animal science meetings in Maryland and Ireland and to a Veterinary Respiratory Disease Conference in Indiana to explain and promote the use of the horse genome information for research. Shared resources, including DNA from reference families, primer sets for investigation of genetic markers and information on databases and reports were distributed to workshop participants, worldwide.
Impact
Collaborative teams have been established within the United States and between scientists within the United States and abroad to conduct research on genetic and physiological traits of horses, including those pertaining to diseases and performance. These teams have already identified specific genes and established tests for coat color traits and several diseases of horses. Work is underway to use measurements of gene transcription to assess hereditary and non-hereditary aspects of disease and performance. We anticipate the extension of these studies in areas of equine nutrition and management as well as the discovery of yet additional genetic markers for hereditary traits.