Publications


 

1. Wang, Z., and Mosbaugh, D. W. (1988) Uracil-DNA glycosylase inhibitor of bacteriophage PBS2: cloning and effects of expression of the inhibitor gene in Escherichia coli. J Bacteriol, 170(3): 1082-1091. 

 

2. Wang, Z., and Mosbaugh, D. W. (1989) Uracil-DNA glycosylase inhibitor gene of bacteriophage PBS2 encodes a binding protein specific for uracil-DNA glycosylase. J Biol Chem, 264(2): 1163-1171. [Full Text]

 

3. Wang, Z., Smith, D. G., and Mosbaugh, D. W. (1991) Overproduction and characterization of the uracil-DNA glycosylase inhibitor of bacteriophage PBS2. Gene, 99(1): 31-37. 

 

4. Wang, Z., Wu, X., and Friedberg, E. C. (1991) Nucleotide excision repair of DNA by human cell extracts is suppressed in reconstituted nucleosomes. J Biol Chem, 266(33): 22472-22478. [Full Text]

 

5. Wang, Z., Wu, X., and Friedberg, E. C. (1992) Excision repair of DNA in nuclear extracts from the yeast Saccharomyces cerevisiae. Biochemistry. 31(14): 3694-3702. 

 

6. Wang, Z., Wu, X., and Friedberg, E. C. (1993) DNA repair synthesis during base excision repair in vitro is catalyzed by DNA polymerase epsilon and is influenced by DNA polymerases alpha and delta in Saccharomyces cerevisiae. Mol Cell Biol, 13(2): 1051-1058.

 

7. Wang, Z., Wu, X., and Friedberg, E. C. (1993) Nucleotide-excision repair of DNA in cell-free extracts of the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A, 90(11): 4907-4911. [Full Text]

 

8. Wang, Z., Svejstrup, J. Q., Feaver, W. J., Wu, X., Kornberg, R. D., and Friedberg, E. C. (1994) Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast. Nature, 368(6466): 74-76. 

 

9. Friedberg, E. C., Bardwell, A. J., Bardwell, L., Wang, Z., and Dianov, G. (1994) Transcription and nucleotide excision repair--reflections, considerations and recent biochemical insights. Mutat Res, 307(1): 5-14. 

 

10. Wang, Z., Wu, X., and Friedberg, E. C. (1995) The detection and measurement of base and excision repair in cell-free extracts of the yeast Saccharomyces cerevisiaeMethods, 7(2): 177-186. [Full Text]

 

11. Svejstrup, J. Q., Wang, Z., Feaver, W. J., Wu, X., Bushnell, D. A., Donahue, T. F., Friedberg, E. C., and Kornberg, R. D. (1995) Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosome. Cell, 80(1): 21-28. [Full Text]

 

12. Wang, Z., Buratowski, S., Svejstrup, J. Q., Feaver, W. J., Wu, X., Kornberg, R. D., Donahue, T. F., and Friedberg, E. C. (1995) The yeast TFB1 and SSL1 genes, which encode subunits of transcription factor IIH, are required for nucleotide excision repair and RNA polymerase II transcription. Mol Cell Biol, 15(4): 2288-2293. [Full Text]

 

13. Wang, X. W., Yeh, H., Schaeffer, L., Roy, R., Moncollin, V., Egly, J. -M., Wang, Z., Friedberg, E. C., Evans, M. K., Taffe, B. G., Bohr, V. A., Weeder, G., Hoejimakers, J. H. J., Forrester, K., and Harris, C. C. (1995) p53 modulation of TFIIH-associated nucleotide excision repair activity. Nature Genet, 10: 188-195.

 

14. Friedberg, E. C., Bardwell, A. J., Bardwell, L., Feaver, W. J., Kornberg, R. D., Svejstrup, J. Q., Tomkinson, A. E., and Wang, Z. (1995) Nucleotide excision repair in the yeast Saccharomyces cerevisiae: its relationship to specialized mitotic recombination and RNA polymerase II basal transcription. Philos Trans R Soc Lond B Biol Sci, 347(1319): 63-68. 

 

15. Wang, Z., Wu, X., and Friedberg, E. C. (1996) A yeast whole cell extract supports nucleotide excision repair and RNA polymerase II transcription in vitro. Mutat Res, 364(1): 33-41. [Full Text]

 

16. Bhatia, P. K., Wang, Z., and Friedberg ,E. C. (1996) DNA repair and transcription. Curr Opin Genet Dev, 6(2): 146-150. 

 

17. Rodriguez, K., Wang, Z., Friedberg, E. C., and Tomkinson, A. E. (1996) Identification of functional domains within the RAD1.RAD10 repair and recombination endonuclease of Saccharomyces cerevisiae. J Biol Chem, 271(34): 20551-20558. [Full Text]

 

18. Wang, Z., Wei, S., Reed, S. H., Wu, X., Svejstrup, J. Q., Feaver, W. J., Kornberg, R. D., and Friedberg, E. C. (1997) The RAD7, RAD16, and RAD23 genes of Saccharomyces cerevisiae: requirement for transcription-independent nucleotide excision repair in vitro and interactions between the gene products. Mol Cell Biol, 17(2): 635-643. [Full Text]

 

19. Feaver, W. J., Henry, N. L., Wang, Z., Wu, X., Svejstrup, J. Q., Bushnell, D. A., Friedberg, E. C., and Kornberg, R. D. (1997) Genes for Tfb2, Tfb3, and Tfb4 subunits of yeast transcription/repair factor IIH. Homology to human cyclin-dependent kinase activating kinase and IIH subunits. J Biol Chem, 272(31): 19319-19327. [Full Text]

 

20. Wang, Z., Wu, X., and Friedberg, E. C. (1997) Molecular mechanism of base excision repair of uracil-containing DNA in yeast cell-free extracts. J Biol Chem, 272(38): 24064-24071. [Full Text]

 

21. Braithwaite, E., Wu, X., and Wang, Z. (1998) Repair of DNA lesions induced by polycyclic aromatic hydrocarbons in human cell-free extracts: involvement of two excision repair mechanisms in vitro. Carcinogenesis, 19(7): 1239-1246. [Full Text]

 

22. Rodriguez, K., Talamantez, J., Huang, W., Reed, S. H., Wang, Z., Chen, L., Feaver, W. J., Friedberg, E. C., and Tomkinson, A. E. (1998) Affinity purification and partial characterization of a yeast multiprotein complex for nucleotide excision repair using histidine-tagged Rad14 protein. J. Biol Chem., 273(51): 34180-34189. [Full Text]

 

23. Braithwaite, E., Wu, X., and Wang, Z. (1999) Repair of DNA lesions: mechanisms and relative repair efficiencies. Mutat. Res., 424(1-2): 207-219. [Full Text]

 

24. Wu, X., and Wang, Z. (1999) Relationships between yeast Rad27 and Apn1 in response to apurinic/apyrimidinic (AP) sites in DNA. Nucleic Acids Res., 27(4): 956-962. [Full Text]

 

25. Lin, W., Wu, X., and Wang, Z. (1999) A full-length cDNA of hREV3 is predicted to encode DNA polymerase zeta for damage-induced mutagenesis in humans. Mutat. Res., 433(2): 89-98. [Full Text]

 

26. Wu, X., Braithwaite, E., and Wang, Z. (1999) DNA ligation during excision repair in yeast cell-free extracts is specifically catalyzed by the CDC9 gene product. Biochemistry, 38(9): 2628-2635. [Full Text]

 

27. Lin, W., Xin, H., Zhang, Y., Wu, X., Yuan, F., and Wang, Z. (1999) The human REV1 gene codes for a DNA template-dependent dCMP transferase. Nucleic Acids Res., 27(22): 4468-4475. [Full Text]

 

28. Yuan, F., Zhang, Y., Rajpal, D. K., Wu, X., Guo, D., Wang, M., Taylor, J. -S., and Wang, Z. (2000) Specificity of DNA lesion bypass by the yeast DNA polymerase eta. J. Biol. Chem., 275(11): 8233-8239. [Full Text]

 

29. Xin, H., Lin, W., Sumanasekera, W., Zhang, Y., Wu, X., and Wang, Z. (2000) The human RAD18 gene product interacts with HHR6A and HHR6B. Nucleic Acids Res., 28(14): 2847-2854. [Full Text]

 

30. Zhang, Y., Yuan, F., Wu, X., and Wang, Z. (2000) Preferential incorporation of G opposite template T by the low fidelity human DNA polymerase i. Mol. Cell. Biol., 20(19): 7099-7108. [Full Text]

 

31. Rajpal, D. K., Wu, X., and Wang, Z. (2000) Alteration of ultraviolet-induced mutagenesis in yeast through molecular modulation of the REV3 and REV7 gene expression. Mutat. Res., 461(2): 133-143. [Full Text]

 

32. Zhang, Y., Yuan, F., Wu, X., Wang, M., Rechkoblit, O., Taylor, J. -S., Geacintov, N. E., and Wang, Z. (2000) Error-free and error-prone lesion bypass by human DNA polymerase k in vitro. Nucleic Acids Res., 28(21): 4138-4146. [Full Text]

 

33. Zhang, Y., Yuan, F., Xin, H., Wu, X., Rajpal, D. K., Yang, D., and Wang, Z. (2000) Human DNA polymerase k synthesizes DNA with extraordinarily low fidelity. Nucleic Acids Res., 28(21): 4147-4156.  [Full Text]

 

34. Zhang, Y., Yuan, F., Wu, X., Rechkoblit, O., Taylor, J. -S., Geacintov, N. E., and Wang, Z. (2000) Error-prone lesion bypass by human DNA polymerase h. Nucleic Acids Res., 28(23): 4717-4724. [Full Text]

 

35. Zhang, Y., Yuan, F., Wu, X., Taylor, J. -S., and Wang, Z. (2001) Response of human DNA polymerase i to DNA lesions. Nucleic Acids Res., 29(4): 928-935. [Full Text]

 

36. Wu, X., Guo, D., Yuan, F., and Wang, Z. (2001) Accessibility of DNA polymerases to repair synthesis during nucleotide excision repair in yeast cell-free extracts. Nucleic Acids Res., 29(14): 3123-3130. [Full Text]

 

37. Guo, D., Wu, X., Rajpal D. K., Taylor J. -S., and Wang, Z. (2001) Translesion synthesis by yeast DNA polymerase z from templates containing lesions of ultraviolet radiation and acetylaminofluorene. Nucleic Acids Res., 29(13): 2875-2883. [Full Text]

 

38. Wang, Z. (2001) Translesion synthesis by the UmuC family of DNA polymerases. Mutat. Res., 486(2): 59-70. [Full Text]

 

39. Ohmori, H., Friedberg, E. C., Fuchs, R. P. P., Goodman, M. F., Hanaoka, F., Hinkle, D., Kunkel, T. A., Lawrence, C. W., Livneh, Z., Nohmi, T., Prakash, L., Prakash, S., Todo, T., Walker, G. C., Wang, Z., and Woodgate, R. (2001) The Y-family of DNA polymerases. Mol Cell, 8(1): 7-8. [Full Text]

 

40. Burgers, P. M., Koonin, E. V., Bruford, E., Blanco, L., Burtis, K. C., Christman, M. F., Copeland, W. C., Friedberg, E. C., Hanaoka, F., Hinkle, D. C., Lawrence, C. W., Nakanishi, M., Ohmori, H., Prakash, L., Prakash, S., Reynaud, C. A., Sugino, A., Todo, T., Wang, Z., Weill, J. C., and Woodgate, R. (2001) Eukaryotic DNA polymerases: proposal for a revised nomenclature. J. Biol. Chem., 276(47): 43487-43490. [Full Text]

 

41. Zhang, Y., Wu, X., Yuan, F., Xie, Z., and Wang, Z. (2001) Highly frequent frameshift DNA synthesis by human DNA polymerase m, Mol. Cell. Biol., 21(23): 7995-8006. [Full Text]

 

42. Wang, Z. (2001) DNA damage-induced mutagenesis: a novel target for cancer prevention. Mol. Interv., 1(5): 269-281. [Full Text]

 

43. Singer, B., Medina, M., Zhang, Y., Wang, Z., Guliaev A. B., and Hang, B. (2002) 8-(Hydroxymethyl)-3,N4-etheno-C, a potential carcinogenic glycidaldehyde product, miscodes in vitro using mammalian DNA polymerases. Biochemistry, 41(6): 1778-1785. [Full Text]

 

44. Zhang, Y., Wu, X., Rechkoblit, O., Geacintov, N. E., Taylor, J. -S., and Wang, Z. (2002) Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion. Nucleic Acids Res., 30(7): 1630-1638. [Full Text]

 

45. Zhang, Y., Wu, X., Guo, D., Rechkoblit, O., and Wang, Z. (2002) Activities of human DNA polymerase k in response to the major benzo[a]pyrene DNA adduct: error-free lesion bypass and extension synthesis from opposite the lesion. DNA Repair, 1(7): 559-569. [Full Text]

 

46. Rechkoblit, O., Zhang, Y., Guo, D., Wang, Z., Amin, S., Krzeminsky, J., Louneva, N., and Geacintov, N. E. (2002) Translesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases. J. Biol. Chem., 277(34): 30488-30494. [Full Text]


47. Zhang, Y., Wu, X., Guo, D., Rechkoblit, O., Taylor, J. -S., Geacintov, N. E., and Wang, Z. (2002) Lesion bypass activities of human DNA polymerase m. J. Biol. Chem., 277: 44582-4587.  [Full Text]

 

48. Zhang, Y., Wu, X., Guo, D., Rechkoblit, O., Geacintov, N. E., and Wang, Z. (2002) Two-step error-prone bypass of the (+)- and (-)-trans-anti-BPDE-N2-dG adducts by human DNA polymerases h and k. Mutat. Res., 510: 23-35[Full Text]  

 

49.  Huang, X., Kolbanovskiy, A., Wu, X., Zhang, Y., Wang, Z., Zhuang, P., Amin, S., 2003. Geacintov, N. E. Effects of base sequence context on translesion synthesis past a bulky (+)-trans-anti-B[a]P-N2-dG lesion catalyzed by the Y-family polymerase pol k.  Biochemistry 42: 2456-2466. [Full Text]  

 

50.  Yang, I.-Y., Miller, H., Wang, Z., Frank, E. G., Ohmori, H., Hanaoka, F., and Moriya, M. 2003. Mammalian translesion DNA synthesis across an acrolein-derived deoxyguanosine adduct: participation of pol η in error-prone synthesis in human cells.  J. Biol. Chem. 278: 13989-13994.  [Full Text]

 

51.  Sun, L., Zhang, K., Zhou, L., Hohler, P., Kool, E. T., Yuan, F., Wang, Z., and Taylor, J. S. 2003. Yeast Pol h holds a cis-syn thymine dimer loosely in the active site during elongation opposite the 3’-T of the dimer, but tightly opposite the 5’-T. Biochemistry 42: 9431-9437.  [Full Text]

52.  Xie, Z., Braithwaite, E., Guo, D., Zhao, B., Geacintov, N. E, and Wang, Z.  2003. Mutagenesis of benzo[a]pyrene diol epoxide in yeast: requirement for DNA polymerase z and involvement of DNA polymerase h. Biochemistry 42:11253-11262.  [Full Text]  

53. Lee, J. W., Blanco, L., Zhou, T., Garcia-Diaz, M., Bebenek, K., Kunkel, T. A., Wang, Z., and Povirk, L. F. 2004. Implication of DNA polymerase l in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts. J. Biol. Chem. 279: 805-811.  [Full Text]   

54. Guo, D., Xie, Z., Shen, H., Zhao, B., and Wang, Z. 2004. Translesion synthesis of acetylaminofluorene-dG adducts by DNA polymerase z is stimulated by yeast Rev1 protein. Nucleic Acids Res. 32: 1122-1130.  [Full Text]

55.  Zhao, B., Xie, Z., Shen, H., and Wang, Z.  2004. Role of DNA polymerase h in the bypass of abasic sites in yeast cells. Nucleic Acids Res. 32: 3984-3994. [Full Text]

56.  Xie, Z., Liu, S., Zhang, Y., and Wang, Z. 2004. Roles of Rad23 protein in yeast nucleotide excision repair. Nucleic Acids Res. 32: 5981-5990. [Full Text]   

57.  Wang, Z. 2005. Mechanism of bypass polymerases in eukaryotes. p. 475-493. In “DNA Damage Recognition”, ed. Siede, W., Kow, Y.W., and Doetsch, P. W. CRC Press, New York, NY. 

58.  Xie, Z., Zhang, Y., Guliaev, A. B., Shen, H., Hang, B., Singer, B., and Wang, Z. 2005. The p-benzoquinone DNA adducts derived from benzene are highly mutagenic. DNA Repair 5: 1399-1409.  [Full Text]. 

59.  Wang, Z. 2006. Controlled expression of recombinant genes and preparation of cell-free extracts in yeast.  p. 317-331. In “Methods in Molecular Biology, vol. 313: Yeast Protocols, 2nd Edition, ed. Xiao, W. Humana Press, Inc., Totowa, NJ. 

60.  Zhao, B., Wang, J., Geacintov, N. E., and Wang, Z. 2006. Polh, Polz, and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells. Nucleic Acids Res. 34: 417-425. [Full Text]

61.  Zhou, Y. Kou, H., and Wang, Z. 2007. Tfb5 interacts with Tfb2 and facilitates nucleotide excision repair in yeast. Nucleic Acids Res. 35: 861-871. [Full Text].

62.  Wang, Z. 2008. DNA Damage and Mutagenesis.  p. 441-491. In “Molecular and Biochemical Toxicology”, 4th Edition, ed. Smart, R. C. and Hodgson, E. John Wiley & Sons, Inc., Hoboken, New Jersey.

63.  Kou, H., Zhou, Y., Gorospe, R. M. C., and Wang, Z. 2008. Mms19 protein functions in nucleotide excision repair by sustaining an adequate cellular concentration of the TFIIH component Rad3. Proc. Natl. Acad. Sci. USA. (in press). 

 

 


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