Boone county was formed in 1799. It is located in the Outer Bluegrass region of the state. The elevation in the county ranges from 455 to 964 feet above sea level. In 2010 the county population was 118,811 in a land area of 246.36 square miles, an average of 482.3 people per square mile.

The county seat is Burlington.

The largest city in the county is Florence. Boone county is in the northern Kentucky area.