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UK Chandler Medical Center Announces Major Women’s Health Initiative


By Vikki Franklin and Maureen McArthur

LEXINGTON, KY (Nov. 21, 2000) – The University of Kentucky Chandler Medical Center is formalizing a major initiative to tackle women’s health issues in Kentucky, officials announced today.  Included in the initiative are the establishment of a Women’s Health Center and the awarding of several large research grants to study women’s health issues.

The initiative tackles women’s health issues through research, clinical, service, educational and leadership efforts.

“The University of Kentucky is proud to be on the forefront, both on a statewide and a national basis, of addressing women’s health issues,” said UK President Charles T. Wethington Jr.

“We are excited that the years of work that have gone into building this initiative from the ground up have paid off in the formation of an official center and in the awarding of several large research grants,” said James W. Holsinger Jr., M.D., Ph.D., chancellor of the UK Chandler Medical Center.  “This is something we are pleased to be able to do for the women of Kentucky and the nation.”

A key component of the initiative is the official establishment of the UK Women’s Health Center, a designation granted by the UK Board of Trustees at its October meeting.  The result of five years of organization and planning, the Center is the first of its kind in Kentucky.

“This is an important medical advance,” said Deborah G. Kwolek, M.D., medical director of the UK Women’s Health Center and an assistant professor of internal medicine in the UK College of Medicine.  “We are putting women’s health on the map, addressing the needs of women in Kentucky as well as nationally.  Kentucky women can be assured their best interests are being addressed here at UK,” Kwolek said.

The initiative also focuses on research to discover scientific and clinical knowledge to understand and improve the health of women.

The UK Chandler Medical Center recently received four major women’s health-related grants totaling more than $15 million over the next five years:

·        A five-year, $8.2 million grant from the National Institutes of Health (NIH) to establish the Center of Biomedical Research Excellence in Women’s Health (COBREWH).  The grant covers administrative functions of the Center and four research projects.  Phyllis Wise, Ph.D., chair of the Department of Physiology at the UK College of Medicine and the Shih Chun Wang Professor (endowed under the Research Challenge Trust Fund Initiative), is the program director.  The UK College of Medicine researchers will examine how estrogen and drugs that are related to estrogen, called selective estrogen receptor modulators (or SERMs), affect women’s neuroendocrine system, ovaries, central nervous and cardiovascular systems, and behavior.  This grant also provides opportunities for junior faculty to receive training in state-of-the-art research techniques to assist them in establishing independent, successful research careers.

·        A five-year, $3.75 million grant from the National Institute on Aging.  The research team, led by Wise, will focus on what happens as women age that prevents the ovaries from functioning as they did during the reproductive years and whether estrogen continues to protect against injury during aging.

·        A three-year, $821,000 grant from the U.S. Department of Education to develop and disseminate a core multidisciplinary women’s health curriculum.  The Multidisciplinary Instructional Models for Women’s Health Education project will be tailored to the needs of each of the five colleges in the UK Chandler Medical Center and disseminated to 15 collaborating institutions nationwide.  Kwolek is the principal investigator for this project. 

·        A five-year, $2.5 million grant from the National Institutes of Health.  The Building Interdisciplinary Research Careers in Women’s Health project will support research on regulation of menopause and its repercussions on women’s health, nutrition-related illnesses and their impact on women, and gender issues and drug abuse. As with the COBREWH grant, this grant also provides opportunities for junior faculty to develop their research careers.  Emery Wilson, M.D., dean, UK College of Medicine, is the principal investigator.  Wise and Claire Pomeroy, M.D., chief of infectious diseases, are the program directors.

On the education front, the initiative includes bringing the new knowledge of gender-based medicine into the curriculum in all five colleges and one school of the Medical Center (medicine, pharmacy, dentistry, nursing, allied health professions, and public health).

“Traditionally, health professions students have been taught everything in relation to a 70-kilogram man – the ‘normal human.’  In the last 10 to 15 years, medical science has begun realizing that there are significant differences between men and women that go beyond reproductive organs,” Kwolek said.

Established in April, Associates in Women’s Health, the clinical portion of the Women’s Health Center, has plans for expansion next year to fill the heavy demand for primary care for women.  A network with other existing UK providers focused on women’s health – such as the Department of Obstetrics and Gynecology, the Comprehensive Breast Care Center and the Ovarian Cancer Screening Program – is being formed.

The initiative also includes efforts to educate the public, other health care professionals and policy-makers.  The Women’s Health Center sponsors an annual women’s health summit, monthly lectures that are broadcast via telemedicine to 13 sites around Kentucky and continuing medical education courses.

“There was very little statewide network-building before we began our efforts,” said Janet Braun, coordinator of the Women’s Health Center.  “Our efforts have encouraged people from across Kentucky to work collaboratively toward a common goal – improving the health of women.”


Comments to Betsy Hall, Last Modified: October 14, 2003
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