Tavist D

Generic Drug
Clemastine fumarate
Phenylpropanolamine Hydrochloride

Dosage Forms (Novartis)

Tablet: Antihistamine: clemastine fumarate (1.34mg), decongestant: phenylpropanolamine hydrochloride (75mg)

• For management of symptoms associated with the common cold, hay fever, or other upper respiratory allergies, nasal congestion, runny nose, sneezing, itching of the nose of throat, and itchy watery eyes. Temporarily relieves nasal congestion associated with sinusitis.
  Oral: Adults and children 12 years of age and over: Swallow one tablet whole every 12 hours, not to exceed two tablets in 24 hours or as directed by a doctor.

Children under 12 years of age: Consult a doctor.

1. Is the patient pregnant or during lactation?

2. What symptoms are present?

3. Does the patient have difficulty in swallowing?

4. Does the patient have hypertension, diabetes, CAD, Asthma?

Instruct the patient not to break the tablets or crush them, but to take the tablets as a whole. This permits the specially designed release system to remain intact. The clemastine is formulated in the outer shell of the tablet and is released immediately. The phenylpropanolamine component is incorporated into a sustained-released matrix, which releases the drug over a period of 12 hour; the slow release achieves blood levels equivalent to those achieved by giving 25 mg phenylpropanolamine q 4 hr for three doses. Report if symptoms do not improve or worsen after 5 days of therapy. Review conditions (hypertension, diabetes, asthma, CAD) in which the drug should be avoided.


Adverse Reactions/Side Effects
Contraindications: children less than 12 years of age and during lactation, treating lower respiratory tract symptoms, including asthma, in patients taking MAO inhibitors or those with severe CAD or hypertension. Use in patients Use in asthma, diabetes, glaucoma, heart disease, emphysema, chronic pulmonary disease, SOB, difficulty in breathing, or prostatic hypertrophy. Not for use for hypertension or depression, unless prescribed by doctor. Do not take this product if on MAOI or two weeks after stopping MAOI drug. or drugs for Parkinson's disease.

May cause drowsiness; alcohol, sedatives, and tranquilizers may increase the drowsiness effect. Avoid alcoholic beverages while taking this product. May cause excitability especially in children. Use caution when driving a motor vehicle or operating machinery. If nervousness, dizziness, or sleeplessness occurs discontinue use and consult a doctor.


Natural Products or Nutritional Interactions (if applicable)
May be taken with food if GI upset occurs. Avoid alcohol while taking this medication.