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Adult Dosing Guidelines
- 325-500mg q3h
- 325-650mg q4h
- 650-1000mg q6h
Pediatric Dosing Guidelines
Not recommended in children due to risk of Reye’s syndrome and availability of safer alternatives.
Triage Questions About Treatment or Related Issues
- Is the patient under the age of 12 years, if yesà Refer to physician.
- Is the patient pregnant, if yesà Salicylates are prohibited, refer to physician.
- Does the patient have allergic reactions to salicylates, if yesà Recommend acetaminophen.
- Is the patient asthmaticà Salicylates contraindicated
- Does the patient have stomach problems that persist or recur, ulcers, or bleeding problems, if yesà Salicylates contraindicated.
- Is the patient taking prescription medications for anti-coagulation, diabetes mellitus, gout, or arthritis, if yesà Salicylates contraindicated.
- Is the patient (child/teenager) recovering from chicken pox or influenza.
General Information
- This drug is hydrolyzed to salicylic acid in the body. It lowers elevated body temperature through vasodilatation of peripheral vessels that enhances dissipation of excess heat. The anti-inflammatory and analgesic activity may be mediated through inhibition of the prostaglandin synthetase enzyme complex.
- Salicylates must not be given below age 2 due to risk of Reye’s syndrome.
- Patients should not take salicylates during last 3 months of pregnancy, due to risk of complications during delivery.
- Patients should not take salicylates if they use blood-thinning products.
- Patients should not take salicylates if they have salicylate allergies.
- Patients should consult a physician if ringing in the ears occurs.
- Heavy drinkers should not take more then 4 grams of salicylates per day.
Adverse Reactions/Side Effects
Reye’s syndrome, hives, rash, nausea, dyspepsia, melena, prolonged bleeding time, hepatic dysfunction with large doses.
Natural Products or Nutritional Interactions
Increases effect of Gingko, Eicosapentaenoic and decosahexaenoic acid (EPA/DHA). |