Dosage Forms (Warner Lambert Consumer, Parke-Davis)
Capsules: Benadryl Allergy Kapseals, soft gel 25mg; Dye-free allergy, LiquiGels 25mg
Adult Dosing Guidelines
Oral: 25 to 50 mg every 4 to 8 hours. Maximum 300mg/day.
Pediatric Dosing Guidelines
Triage Questions About Treatment or Related Issues
·Do you plan to drive/operate heavy machinery while taking this medication?
·Are you taking any other medication (specifically other depressants or alcohol)?
·Do you have any other current conditions (asthma, glaucoma, are you nursing)?
Diphenhydramine competitively inhibits histamine at the H1 receptor site. Antihistamines will prevent, but not reverse, histamine-mediated reactions. It is nonselective, acting on both central and peripheral H1 receptors to decrease reactions such as flaring and itching. Therapeutic effects begin to occur 15-30 minutes after administration and last for 4-6 hours. Peak effects are seen 1-2 hours after administration. Use is contraindicated in patients with lower respiratory tract symptoms (including asthma), nursing women, narrow-angle glaucoma, stenosing peptic ulcer, the elderly and debilitated, and children under 6 months. Caution should be taken with patients with an enlarged prostate causing difficult urination or children under 6. Consult a physician if the patient is nursing or pregnant. Caution should be taken in operating a motor vehicle or heavy machinery.