Jan Pyrek
Ph.D.

Representative Publications

ON BILE ACIDS:
Pyrek J. St., Lee S.P., Thomase L., Tasman-Jones C., and Leydon B., Bile acids of marsupials 2. Hepatic formation of vulpecholic acid (1a, 3a, 7a-trihydroxy-5b-cholan-24-oic acid) from chenodeoxycholic acid in a marsupial trichosurus vulpecula (Lesson). J. Lipid Res., 32, 1417-1428 (1991)

Radominska A., Little J., Pyrek J. St., Drake R., Igari Y., Fournel-Gigleux S. Magdalou, Burchell E., Siest, and Lester R. A novel UDPG1c-specific glucosyltransferase catalyzing the biosynthesis of 6-0-glucosides of bile acids in human liver microsomes. J. Biol Chem., 268, 15127-15135 (1993)

ON NATURAL PRODUCTS:
Snyder J.C., Guo Z., Thacker R., Goodman J.P., and Pyrek J. St., 2, 3-Dihydrofarnesoic acid, a unique terpene from trichomes of Lycopersicon hirsutum, repels spider mites. J. Chem. Ecol., 19, 2981-2990 (1993)

Pyrek J.St., Aggarval S.K., Barboza P., Goodman J.P., and Yang P-Y, Metabolites of nuatigenin (22S,25S) 22, 25-epoxy-3b, 26-dihydroxy-furost-5-ene)  accumulate in the bile of rabbits fed oats. in "Saponins Used in Traditional and Modern Medicine," Advances in Experimental Medicine and Biology: "Saponins Used in Food and Agriculture," edited by G.R. Waller and K. Yamasaki. Plenum Press Publishing C. (1996) pp 443-458

ON PEPTIDES:
Csuhai E., Juliano M.A., Pyrek J. St., Harms A.C., Juliano L., and Hersh L.B., "New fluorogenic substrates for N-arginine dibasic convertase," Analytical Biochemistry, 269, 149-154 (1999)

Chow K.M., Csuhai E., Juliano M.A., Pyrek J. St., Juliano L., Hersh L.B., Studies on the subsite specificity of rat nardilysin (N-arginine dibasic convertase). J. Biol. Chem., in press (2000)

Research Interests | Return to Dr. Pyrek's main page