Acyclovir

• Dosing regimens

  • Oral - 200 - 4000 mg/day in divided doses.
  • I.V. - 5-20 mg/kg - every 8 hours.

• Drug interactions

  • AZT - increased CNS toxicity
  • Cyclosporin - increased renal toxicity
  • Decreases renal clearance of other drugs.

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