Dr. Thomas Dziubla
(Fall 2013) University of Kentucky
Current cover October, 2013 of Biomaterials Forum quarterly newsletter of the Society for Biomaterials
On the cover: Layer-by-layer networks of methoxy-poly(ethylene glycol)-b-poly(lactic acid) filomicelles(FM). Networks were formed by the alternate deposition of biotinylated-FM and streptavidin. (Top image - 1 layer, Bottom image and SEM - 7 layers) The resulting layers form a mucin-like network that can be loaded with hydrophobic drugs or surface decorated with active proteins, serving as an artificial replacement of a mucosal surface. Fluorescence imaging was obtained by the naturally fluorescent antioxidant, curcumin, loaded into the FM as a model drug. This material was developed by Sundar Authimoolam in the research group of Thomas Dziubla in the Department of Chemical and Materials Engineering at the University of Kentucky.