The Graduate Center for Toxicology, established as a degree-granting program in 1969, has graduated approximately 140 students with a Ph.D. in Toxicology and have gone on to productive careers in academia, government, and industry.  Below are a few:

1985 – Michael Graziano - Executive Director, Drug Safety   Evaluation, Bristol-Myers Squibb

Dr. Graziano is responsible for all personnel, operations, and toxicology studies performed in Drug Safety Evaluation at two major Bristol-Myers Squibb facilities. These two sites conduct toxicology studies for investigational drugs in the following therapeutic areas: cardiovascular disease, metabolic disease, and diseases of the central nervous system.

1986 – Michael Hughes— US EPA - Pharmacokinetics

1987 – William Mundy – US EPA – Neurotoxicology

Dr. Mundy is a Neurotoxicologist with the Cellular and Molecular Toxicology Branch of the National Health and Environmental Effects Research Laboratory, U.S. EPA.  His primary research interests include the effects of toxic chemicals on intracellular signaling in the nervous system and the use of in vitro models to assess the effects of toxicants on neuronal development and synaptic plasticity.

E-mail: Michael.graziano@bms.com

E-mail: mundy.william@epa.gov

1989 – Jana Cox Henson – Georgetown College

Dr. Henson is the lab coordinator for the biology department at Georgetown College.  She also teaches courses in both the biology and chemistry departments at this small liberal arts school just up the road from UK.

E-mail: Jana_Henson@georgetowncollege.edu

1993 – Vickie Tatum – National Council for Air and Stream Improvement, Inc.

Dr. Tatum is the only toxicologist on staff and uses her knowledge to support other programs.  Past projects include identifying synergistic effects of herbicide mixtures on aquatic organisms, measuring levels of airborne wood dust in wood products mills, preparing a literature review on the aquatic toxicity of wood and bark leachates, and preparing a report on the health effects of odorous emissions from industrial facilities

E-mail: v_tatum@src-ncasi.org

1999 – Bert Watson – Johns Hopkins

Dr. Watson is a tenure track Assistant Professor in the Division of Toxicological Sciences within the Department of Environmental Health Sciences at Johns Hopkins Bloomberg School of Public Health.  His laboratory focuses on the role of reversible protein oxidation and reduction in molecular mechanisms of toxicological responses.

E-mail: wwatson@jhsph.edu

2000 – Brian Laden – Vanderbilt U, Technology Transfer

Dr. Laden works in the Office of Technology Transfer and Enterprise Development at Vanderbilt. He manages patent prosecution, market technologies and negotiates license deals with companies ranging from start-ups to big pharma.  He also helps start companies through the office's venture investment activites.

E-mail: brian.p.laden@Vanderbilt.Edu

2002 – Scott McCulloch – NIEHS  (Postdoc)

Dr. McCulloch is working on translesion DNA synthesis, specifically how polymerase Eta interacts with and is affected by both damaged DNA and replication accessory proteins. They are hoping to better understand how a low-fidelity polymerase (Pol Eta) suppresses sunlight induced skin cancer, and also to understand how cells choose which of the currently known 16 polymerases is best suited for a given DNA transaction.

E-mail: mccullo2@mail.nih.gov

2005 - Tracy Henriques – Duke U   (Postdoc)

Dr. Henriques is a post-doc at Duke University in the College of Medicine, Nephrology Division under division chair Thomas Coffman, MD.  She is studying the interaction between the renin angiotensin system and prostaglandins in the development of renal and cardiovascular pathologies.

E-mail: tracy.henriques@duke.edu

Dr. Hughes is a Toxicologist with the National Health and Environmental Effects Research Laboratory, US EPA. He works in the Pharmacokinetics Branch, and conducts laboratory research on the disposition (ADME) of chemicals found (arsenic) or used in our environment (pesticides). The research is conducted to support decisions made by the regulatory offices of the US EPA.

E-mail: hughes.michaelf@epa.gov

2004 - Xabier Arzuaga — UK (Postdoc)

Dr. Arzuaga is a post-doc at the University of Kentucky in the laboratory of Dr. Bernhard Hennig.  He is working under the Superfund Basic Research Program.  His research deals with the interactions between environmental pollutants, PCBs, and nutrition and their roles in regulating/stimulating inflammatory signaling leading to cardiovascular disease.

E-mail: xarzu2@uky.edu

2003 – Janelle Crossgrove – Purdue University (Postdoc)

Dr. Crossgrove is now a post-doc at Purdue University in the School of Health Sciences.  Her recent research paper was selected to be the 2005 best paper award in the category of ‘experimental biology’ for the Society of Experimental Biology in Medicine.  The paper is entitled “The choroid plexus removes beta-amyloid from brain cerebrospinal fluid.” (Exp Biol Med. 2005 Nov: 230(10): 771-6).