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Anna Rothert Raines

Whole-cell-reporter-gene-based biosensing systems on a compact disk microfluidics platform
Mentor: Dr. Sylvia Daunert

Anna's Beckman research proposal can be found at the bottom of the page.

Since graduating from the University of Kentucky in 2004 with duel degrees in Biology and Chemistry, Anna has received her doctorate degree in Nutritional Sciences from the University of Wisconsin. She is currently working as a post-doctoral fellow at the Cincinnati Children's Hospital in the Developmental Biology research unit.


BMC Genomics
Selenium Toxicity but not Deficient or Super-nutritional Selenium Status Vastly Alters the Transcriptome in Rodents

Bioscience Reports
Selenium status highly-regulates selenoprotein mRNA levels for only a subset of the selenoproteins in the selenoproteome

Society for Experimental Biology and Medicine
Selenium Requirements are Higher for Glutathione Peroxidase-1 mRNA than Gpx1 Activity in Rat Testis

The Journal of Nutrition
Transcript Analysis of the Selenoproteome Indicates that Dietary Selenium Requirements of Rats Based on Selenium-regulated Selenoprotein mRNA Levels are Uniformly Less than those Based on Glutathione Peroxidase Activity

Analytical Biochemistry
Whole-cell-reporter-gene-based biosensing systems on a compact disk microfluidics platform

Professional Conference Presentations:

2004 - Delegate, 8th World Congress on Biosensors, Granada, Spain
2004 - University of Kentucky Undergraduate Chemistry Poster Competition, honorable mention
2003 - 55th Souheast Regional Meeting of the American Chemical Society (SERMACS), Atlanta,

GA, second place, UG poster competition

From Anna (Spring 2004):

I grew up in Northern Kentucky and attended high school at Notre Dame Academy in Park Hills, Kentucky. I am currently a senior Honors Student and National Merit Scholar here at UK, pursuing a double major in Biology and Chemistry. Though I have changed my major and added one since enrolling at the university, I am still managing to graduate on time in May 2004. My decision to switch from my initial choice of Engineering to the life sciences was made after I worked for a semester as a lab technician in the Analytical Chemistry lab of Dr. Sylvia Daunert.

I became quite interested in the research going on in the lab, and soon I was working on my own project for credit as a part of Biology 395. My project involves investigating an innovative method for detection of environmental pollutants, such as arsenic. This sensing system utilizes bacterial cells that produce a fluorescent protein in the presence of small amounts of the toxin.

When I heard about the Beckman Scholars program, I was excited about the possibility of continuing my work under the funding it would provide. So far, I have had a wonderful experience with the program and have been able to accomplish a great deal that would not have been possible without its support. Being a part of this program has enriched my experience as an undergraduate at UK, and has prepared me well for what lies ahead.

Upon graduation, I plan to pursue graduate school in Molecular and Biochemical Nutrition. Recognizing how our bodies use and are affected by what we eat is fundamental to an understanding of health in general. Nutritional crises are rampant worldwide with problems on both extremes of consumption. These are problems that will require more understanding and more education for all people.

I have been an athlete all of my life, and this is another reason why nutrition is so important to me. I have played volleyball competitively for 10 years, 3 of which were on the UK Club volleyball team. I also enjoy running, hiking, traveling and reading.

Research Proposal: