Banner Link to UK Academy for Undergraduate Excellence Division of Undergraduate Education

The Office of Undergraduate Research

Laura Crawford (Cleary)

A Novel Methodology to Identify Chondroitin Sulfate Proteoglycan Microstructures that Inhibit Neuronal Regeneration
Mentor: Dr. Diane Snow

Laura's Beckman research proposal can be found at the bottom of the page.

Laura graduated from the University of Kentucky in 2010 with a Bachelor's Degree in Agricultural Biotechnology.  She is currently a 3rd-year medical student at the University of Kentucky.

Professional Conference Presentations as a Beckman Scholar:

Crawford, L.C., Curinga, G.M., Calulot, C.M., Huynh, T-D., Hering, T.M., and Snow, D.M., Binding of "designer" chondroitin sulfate proteoglycans in vitro to analyze inhibition of axonal regeneration. Beckman Conference, July 22-24, 2010, Irvine, CA

Crawford, L.C., Curinga, G.M., Calulot, C.M., Huynh, T-D., Hering, T.M., and Snow, D.M. A methodology to determine binding of chondroitin sulfate proteoglycan variants in an inhibition assay. 28th Natl Neurotrauma Soc Symp, Las Vegas, NV; June. 13-17, 2010

Snow, D.M., Curinga, G.M., Calulot, C. M., Crawford, L.C., Bahrami, A.,  Huynh. T-D.,  and Hering, T.M. Sensory Neuron Growth Cone Morphology Serves As A Biological Read-Out For Subtle Variations In Chondroitin Sulfate Proteoglycan Microstructure. 27th Natl Neurotrauma Soc Symp, Santa Barbara, CA, Sep. 7-11, 2009

Crawford, L.C., Curinga, G. M., Calulot, C., Kobraei, E., Huynh, T.-D., Westerfield, B., Carlson, S, Hering, T.M., and Snow, D.M.  (2009) A Novel Methodology to Identify Microstructures of Chondroitin Sulfate Proteoglycans that Inhibit Regeneration Following Central Nervous System Injury. Southern Regional Honors Conference in St. Petersburg, FL, May 26-28, 2009

Crawford, L.C., Curinga, G. M., Calulot, C., Kobraei, E., Huynh, T.-D., Westerfield, B., Carlson, S, Hering, T.M., and Snow, D.M. (2009) A Novel Methodology to Identify Microstructures of Chondroitin Sulfate Proteoglycans that Inhibit Regeneration Following Central Nervous System Injury. Nat'l Conf Undergrad Res, April 16-18, 2009, University of Wisconsin, La Crosse, Wisconsin

2009 - 15th Annual Spinal Cord and Head Injury Trust Research Symposium, Louiville, KY

Publications Following Graduation from UK:

D'Orazio, J., S. Jarrett, A. Marsch, J. Lagrew and L. Cleary. 2012. "Melanoma - Epidemiology, Genetics and Risk Factors", chapter in "Melanoma - From Early Detection to Treatment", InTech Publishing, ISBN 980-953-307-757-9.

Presentations Following Graduation from UK:

BY Hanaoka, LC Cleary, D Long, CP Starnes, J Duan, Q Fan, C A Peterson, LJ Crofford, Relationship between the American College of Rheumatology (ACR) Classification Criteria of Functional Status and Clinical Predictors of Disability in Inflammatory Myopathies (IIM). The European League Against Rheumatism (EULAR) 2013. Madrid, Spain. Poster Presentation.

BY Hanaoka, LC Cleary, D Long, G Chleboun, LJ Crofford. Utility of ultrasound in assessing skeletal muscle architecture in idiopathic inflammatory myopathies (IIMs). The European League Against Rheumatism (EULAR) 2013. Madrid, Spain. Poster Presentation.

LC Cleary, SR Nester, SR Nimma, ST McElroy, CL Wilson, and S Tobin.  Incontinentia pigmenti: a case report promoting prevention and screening in afflicted neonates. AOA Research Symposium 2013. Lexington, KY. Poster Presentation.

LC Cleary. Clinical Predictors of Fatigability and Maximum Voluntary Isometric Contraction (MVIC) in a Cohort of Patients with Idiopathic Inflammatory Myopathies.  CCTS Research Seminar 2012. Lexington, KY. Oral Presentation.

LC Cleary. Clinical Predictors of Fatigability and Maximum Voluntary Isometric Contraction (MVIC) in a Cohort of Patients with Idiopathic Inflammatory Myopathies.  CCTS Research Seminar 2012. Lexington, KY. Oral Presentation.

Awards and Noteworthy Achievements as a Beckman Scholar:

2010 - Wethington Fellowship
2007-2008 - Chellgren Fellow
2006-2010 - Singletary Scholarship

Awards and Noteworthy Achievements Following Graduation from UK:

2013 - Alpha Omega Alpha Honor Society Executive Board
2013 - Alpha Omega Alpha Honor Society Executive Board
2012 - Irving and Esther Kanner Memorial Award for outstanding performance in the second year in basic sciences and clinical diagnosis, University of Kentucky College of Medicine
2012 - Excellence in Pathology and Laboratory Medicine Award for highest grade in second-year pathology course, University of Kentucky College of Medicine Department of Pathology and Laboratory Medicine
2012 - William R. Martin Award for the highest grade in the second-year pharmacology course, University of Kentucky College of Medicine Department of Molecular and Biomedical Pharmacology

Year: 
2009-2010
Research Proposal: