College of Pharmacy

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Acelagen
1601 Nicholasville Road, Lexington, KY 40503-1470 | 859.278.3226
Develops technology for high-throughput production of a range of DNA products for the biomedical research industry and provides molecular biology support for academic and commercial biomedical research laboratories. Based on the research of Colin Wilson.

Affitech Laboratories
3332 Pastern Court, Lexington, KY 40513-1004
Focuses on isolation of biologically active peptides, hormones and enzymes from E. coli and other microorganisms, and development of enzyme immunoassays for these substances. Provides technology to other pharmaceutical companies for in-house use or for further commercialization. Based on the research of Hsin-Hsiung Tai.

Alcomed
Daniel Wermeling | 859-221-4138
Alcomed is developing a medication, intranasally delivered naloxone, for prevention and treatment of overdose from narcotic medications. The intended populations who could receive the product are patients seen by EMS services, pain management patients, and those who have recently undergone deotoxification, or those who are maintained on methadone or buprenorphine.

Alkymos
Robert Yokel | 859.257.4855
Alkymos designs, synthesizes and manufactures chelators and chelator-based devices for laboratory, industrial, animal and human applications.

AllTranz
www.alltranz.com
Founded in 2004 by Audra Stinchcomb, pharmacy, the company specializes in transdermal delivery methods of drugs, contracts with pharmaceutical companies and consumer product companies to perform the R&D associated with skin-related toxicity testing and transdermal/topical product development.

Artemetrx
www.artemetrx.com
Artemetrx is a healthcare cost containment company that uses data to develop and implement blueprints for health cost savings. Through its secure, web-based, data analysis tool, Artemetrx integrates medical and prescription claims data into a comprehensive real-time analysis of healthcare utilization, outcomes and expenditures.

Bio-Products International Corporation
235 Bolivar Street, Lexington, KY 40508-2931
Founded in 1994, the company develops nucleotide photoaffinity analogs for use as research tools for identifying proteins and in studying DNA/RNA binding proteins at the molecular level. Merged into Affinity Labeling Technologies. Based on the research of Boyd Haley.

CellSignals
1275 Kinnear Road, Columbus, OH 43212-1155 | 614.340.1845
Develops pharmaceuticals by investigating biochemical agents that have the potential to promote hemostasis and stop bleeding in trauma victims. Based on the research of Melissa Shieh.

DeNovo
3233 Raven Circle, Lexington, KY 40502-3305 | 859.257.1718
Founded in 1997, the company develops promising therapeutic agents and brings them to a stage where their safety and efficacy can be assessed. Based on the research of Peter Crooks.

Emagin Therapeutics
Develops new and improved drug entities to treat acute, chronic and cancer-related pain and delivery systems for pain management. Based on research by Joe Holtman MD, anethesiology & pain management, and Peter Crooks.

Four Tigers
www.four-tigers.com
Four Tigers, founded by Paige Shumate Short and researchers from the University of Kentucky, is developing a pipeline of blackberry-based health products that will be marketed as cosmetics, dietary supplements, and foods. Initial products include a topical vanishing blackberry cream, a blackberry oral capsule targeted to the intestines and colon, and a blackberry chewing gum. Four Tigers is also developing an exciting portfolio of medical products harnessing the potent anti-inflammatory and anti-oxidant properties of blackberries. Utilizing blackberries grown at WindStone Farms, researchers at the University of Kentucky have shown that an extract of the blackberries is able to inhibit the growth of human cancer cells in the laboratory. Studies are under way to explore new medical applications, including studies in animals to demonstrate that blackberry extracts can prevent or treat cancer and inflammatory diseases. Based on the research of Russell J. Mumper.

InfraReDx
www.infraredx.com

Insys Therapeutics

Intranasal Technology

K&K Biosciences
2504 Century Lane, Chadds Ford, PA 19317-8960 | 610.399.8625
Founded in 1996, the company develops drugs for various neurological or brain disorders such as epilepsy and Parkinson's disease. Based on the work of P.K. Kadaba.

NanoMed Pharmaceuticals®
7107 Elm Valley Drive, Room B1210, Kalamazoo, MI 49009 | 269.488.8525
NanoMed Pharmaceuticals® is an early-stage specialty pharmaceutical company dedicated to developing improved therapeutic and diagnostic products to treat or detect cancer and other serious diseases. The company's core technology, Nanotemplate Engineering, is a nanoparticle manufacturing technology used to formulate small molecules, peptides, proteins, plasmid DNA, and diagnostic agents. NanoMed was founded in 2000 by Russell J. Mumper and Michael Jay.

New Millennium Pharmaceutical Research
4999 Hartland Parkway, Lexington, KY 40515-1121 | 859.272.8684
Develops nasal-delivery systems for selected medication, including an innovative drug to ease nausea in chemotherapy patients. Based on the research of Anwar Hussain and Lewis Dittert.

Niadyne
2509 North Campbell Avenue #138 Tucson, AZ 85719-3362 | 520.250.7532
Develops topical products designed to enhance skin health and appearance through the prevention and repair of cellular damage. Based on the research of Elaine Jacobson / formerly allied health professions, and Mike Jacobson / formerly pharmacy.

Phoenix Pharmacologics
1517 Nicholasville Road, Suite 402, Lexington, KY 40503-1429 | 859.277.8890
Develops novel biological anti-cancer drug; four drugs that treat eight types of cancer are in clinical development. Based on the research of Mike Clark and inventions from the Ludwig Institute for Cancer Research in San Diego, CA.

Prescient Medical
www.prescientmedical.com
Prescient Medical was founded to commercialize pioneering products for the prevention of heart attacks. Prescient is developing new diagnostic techniques and treatments to match the more comprehensive understanding of arterial pathophysiology defined by the cardiology community. Their robust product development portfolio includes both diagnostic and therapeutic catheter-based devices that will allow interventional cardiologists to more precisely tailor focal treatment according to the unique needs of each patient. Based on the research of Robert Lodder.

Summit Biosciences
www.summitbiosciences.com
Summit Biosciences is developing a synthetic THC nasal spray product with funding from the qualifying therapeutic discovery project program. The nasal spray was developed by pharmacy researcher Dan Wermeling to treat nausea and vomiting associated with cancer chemotherapy. The company recently raised $2 million out of $3.2 million in Series A financing and has 15 full time and 6 part time employees. Summit Biosciences is located at the UK Coldstream Research Campus.

TIgen Pharmaceuticals
235 Bolivar Street, Lexington, KY 40508-2931 | 859.388.9444
Founded in 1998, the company focuses on Topoisomerase Inhibition (TI), for the selective delivery of drugs to target tissues. Based on the research of the late Thomas Burke.

TrackFive Diagnostics
Penni Black | 859.327.4334
Founded in 2009 by Penni Black, TrackFive Diagnostics will develop genomic-based tests to predict how cancer patients will respond to treatment with EGFR inhibitors that are used to treat metastatic colorectal cancer, non-small cell lung cancer, head and neck cancers and pancreatic cancer.

Triboflow Separations
triboflow.com
Developing an innovative technique and sensors to detect in real time the metabolic activity of microbes and cells and their susceptibility to either drug treatments or viral infections. Based on research by John Stencel, Center for Applied Energy Research.

WTT
WTT, founded in 1988, was based on the research of founders David Watt (College of Medicine, cellular and molecular biochemistry), Dan Tai (College of Pharmacy), and Tom Tobin (College of Agriculture, Gluck Equine Research Center). WTT developed enzyme-linked immunosorbent assay (ELISA ) tests for drugs of abuse in race horses and dogs. They had developed 29 diagnostic tests before the company was sold to the international food and animal safety company, Neogen in 1991. Neogen’s Animal Safety Division is based in Lexington, Ky.

Yaupon Therapeutics
www.yaupontherapeutics.com
Yaupon Therapeutics, a specialty pharmaceutical company based on research by Linda Dwoskin and Peter Crooks, develops small molecule pharmaceuticals licensed from academic laboratories. The researchers have had great success with lobeline, an alkaloid from American Indian tobacco, which in animal models blocks the desire for methamphetamine. In 2005, Yaupon was named Life Sciences Startup Company of the Year at the Eastern Technology Council's Annual Enterprise Awards ceremony.

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