Patents

FY 2011 | FY 2010 | FY 2009 | FY 2008 | FY 2007 | FY 2006

UK currently holds 380 patents and a strong portfolio in drug development & design, plant biotech, equine health, and materials for medical implants, drug delivery systems, and medical devices.

2012 Patents (Fiscal Year July 1, 2011 - June 30, 2012)

March 2012

Robert L. Houtz (horticulture) received a patent for “Modified rubisco large subunit n-methyltransferase useful for targeting molecules to the active-site vicinity of ribulose-1,5-bisphosphate” #8,138,309

Peter Palese (Leonia, NJ), Adolfo Garcia-Sastre (New York, NY), Thomas Chambers (veterinary science) received a patent for “Genetically engineered equine influenza virus and uses thereof” # 8,137,676

February 2012

Ralph E. Dewey (Apex, NC), Balazs Siminszky (formerly plant and soil sciences), Steven W. Bowen (Raleigh, NC), Lily Gavilano (formerly plant and soil sciences) received a patent for “Alteration of tobacco alkaloid content through modification of specific cytochrome P450 genes” #8,124,851

Peter A. Crooks (pharmaceutical sciences), Craig T. Jordan (Rochester, NY), Xiaochen Wei (pharmaceutical sciences) received a patent for “Use of parthenolide derivatives as antileukemic and cytotoxic agents” #8,124,652

Subba Reddy Palli (entomology), Ajay Kumar Singh (plant pathology) received a patent for “Gene expression modulation system for use in plants and method for modulating gene expression in plants” #8,115,059

Elaine L. Jacobson (formerly nutritional sciences), Myron K. Jacobson (formerly pharmaceutical sciences), Hyuntae Kim (Tucson, AZ), Donna L. Coyle (Tucson, AZ), William R. Coyle (Tucson, AZ) received a patent for “Method for treating hair growth disorders, such as female pattern alopecia, and compositions useful therefore” # 8,114,390

Gary Van Zant (medicine), Ying Liang (medicine) receive a patent for “Ex vivo and in vivo methods and related compositions for generating hematopoietic stem cell populations” # 8,110,184

January 2012

Ernest Bailey (veterinary science) and Samantha A. Brooks (formerly veterinary science), received a patent for “Method for screening for a tobiano coat color genotype” #8,101,354

Peter A. Crooks (formerly pharmaceutical sciences) and Ashish Pramod Vartak (formerly pharmaceutical sciences) received a patent for “Enantioselective synthesis of (+) and ( )-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene”  #8,101,779

Joseph Chappell (plant and soil sciences) and Kyoungwhan Back (Pukgu, KR) received a patent for “Chimeric isoprenoid synthases and uses thereof” #8,106,260

November 2011

Bradley D. Anderson and Tian-Xiang Xiang (pharmaceutical sciences), Vijay Joguparthi (formerly pharmaceutical sciences), “Liposomal, ring-opened camptothecins with prolonged, site-specific delivery of active drug to solid tumors” # 8,067,432

Robert A. Yokel and Chang-Guo Zhan (pharmaceutical sciences), Wesley R. Harris and Christopher D. Spilling (St. Louis, Mo.), “Removing aluminum from solution using chelating compounds and immobilized tethered chelators” #8,066,883

David Hildebrand, Suryadevara Rao and John Thoguru (plant and soil sciences), “Fungal desaturases and related methods” #8,053,633

October 2011

Michael Jay and Russell J. Mumper (formerly pharmaceutical sciences), “Methods and pharmaceutical compositions for decorporation of radioactive compounds” #8,030,358

Nasr A. Shuaib (formerly mechanical engineering), Marwan Khraisheh (mechanical engineering), “Method and apparatus for characterizing microscale formability of thin sheet materials” #8,042,405

September 2011

Joe Chappell (plant and soil sciences), Shuiqin Wu (plant and soil sciences), Michel Schalk (Collonges-Sous-Saleve, FR), Athony Clark (West Windsor, NJ), “Transformed plants accumulating terpenes” #8,017,835

Udeni B. R. Balasuriya (veterinary science, MH Gluck Equine Research Center), Peter J. Timoney (veterinary science), Jianqiang Zhang (veterinary science), “Infectious cDNA clone of the modified live virus vaccine strain of Equine arteritis virus” # 8,012,735

August 2011

Jayakrishna Ambati (ophthalmology and visual science), “CCR3 inhibition for ocular angiogenesis and macular degeneration” # 8,008,092

July 2011

Dennis P. Curran (Pittsburgh, PA), David Bom (Pittsburgh, PA), Thomas G. Burke (deceased, formerly pharmaceutical sciences), “Camptothecin analogs and methods of preparation thereof” # 7,982,041

Joe Chappell (plant and soil sciences), Shigeru Okada (Tokyo, JP), Tom Niehaus (plant and soil sciences), Tim Devarenne (Bryan, TX), “Botryoccocus braunii triterpene synthase proteins and nucleic acid molecules, and methods for their use” #7,985,568

2011 Patents

29 patents were issued to UK in Fiscal Year 2011.

June 2011

Thomas L. Robl and John Groppo (Center for Applied Energy Research), “Method for hydraulically separating carbon and classifying coal combustion ash” #7,963,398

Russell J. Mumper (pharmacy), Jin Dai (Carrboro, NC), Vincent S. Gallicchio (Allied Health Professions), “Berry preparations and extracts” #7,964,223

Michael E. Kalinski (civil engineering), "Lightweight inflatable borehole receiver unit for seismic testing" # 7,954,595

April 2011
Robert A. Yokel and Chang-Guo Zhan (pharmaceutical sciences), Wesley R. Harris and Christopher D. Spilling (St. Louis, MO), "Chelating compounds and immobilized tethered chelators" # 7,932,326

Jayakrishna Ambati (ophthalmology and visual sciences), "Methods and animal model for analyzing age-related macular degeneration" # 7,928,284

Patrick G. Sullivan (anatomy and neurobiology), "Nanotubes as mitochondrial uncouplers" # 7,919,699

Chang-Guo Zhan, Hoon Cho and Hsin-Hsiung Tai (pharmaceutical sciences), "High-activity mutants of butyrylcholinesterase for cocaine hydrolysis and method of generating the same" # 7,919,082

February 2011
Manuel Castillo (biosystems and agricultural engineering), Colette C. Fagan (Glasnevin, IE), Colm P. O'Donnell (Clonskeagh, IE), Donal J. O'Callaghan (Whites Cross, IE), Frederick Alan Payne (biosystems and agricultural engineering), "Online, continuous sensor and method for curd moisture content control in cheese making" # 7,892,584

Chang-Guo Zhan (pharmaceutical sciences), Fang Zheng (pharmaceutical sciences), Wen Chao Yang (pharmaceutical sciences), "High activity mutants of butyrylcholinesterase for cocaine hydrolysis" # 7,892,537

Christopher Dwight Thompson (agriculture), Suraj M. Alexander (Anchorage, Ky.), William L. Crist (animal and food sciences), Brian D. Luck (biosystems and agricultural engineering), James Ryan Moore (Beaver Dam, Ky.), Jonathan C. Paschal (Alvaton, Ky.), Frederick Alan Payne (biosystems and agricultural engineering), Timothy S. Stombaugh (biosystems and agricultural engineering), Nasrin Tabayehnejad (biosystems and agricultural engineering) Phillip C. Womble (White House, Tenn.), "Security monitoring system for a bulk foodstuff transport container" # 7,886,959

Ralph E. Dewey (Apex, N.C.), Steven W. Bowen (Raleigh, N.C.), Balazs Siminszky and Lily Gavilano (formerly plant and soil sciences), "Alteration of tobacco alkaloid content through modification of specific cytochrome P450 genes" # 7,884,263

Colm D. Everard (Thurles, IE), Donal J. O'Callaghan (White Cross, IE), Colm P. O'Donnell (Consicegh, IE), Colleen C. Fagan (Giasnevin, IE), Manuel Castillo (biosystems and agricultural engineering), Frederick Alan Payne (biosystems and agricultural engineering), "Method of improving cheese quality" # 7,880,881

January 2011
Stephen L. Dobson (entomology), "Transfected mosquito vectors" # 7,868,222

Tae H Ji (chemistry), Inhae Ji (formerly chemistry), "Methods and compositions for treating neurological disorders" # 7,867,978

December 2010
Omofolami Tesileem Ladipo (chemistry), Richard Eaves (Lexington, Ky.), Alexey Zazybin (Kazan, RU), Sean Parkin (chemistry), "Precatalysts useful in polyolefin polymerization reactions" # 7,851,570

Mark A. Lovell and Bert C. Lynn (chemistry), "Biomarkers of mild cognitive impairment and alzheimer's disease" # 7,851,172

November 2010
Laurence G. Hassebrook and Daniel L. Lau (electrical and computer engineering), Chun Guan (engineering), "System and technique for retrieving depth information about a surface by projecting a composite image of modulated light patterns" # 7,844,079

Bruce Webb and Jeremy Kroemer (agriculture), "Cell lines having enhanced cell longevity and protein expression" # 7,842,493

October 2010
Jayakrishna Ambati (ophthalmology and visual science), "Compositions and methods for inhibiting drusen complement components C3a and C5a for the treatment of age-related macular degeneration" # 7,816,497

Peter A. Crooks (pharmaceutical sciences), Aimee K. Bence and David R. Worthen (Lexington, Ky.), "Agmatine and agmatine analogs in the treatment of epilepsy, seizure, and electroconvulsive disorders" # 7,816,407

Susan C. Straley, Tanya Myers-Morales and Robert D. Perry (microbiology and immunology), Brian S. Murphy (internal medicine), Stanislav Forman (Santa Ana, Calif.), Christine R. Wulff (Columbia, S.C.), "Compositions and methods for treating Yersinia pestis infection" # 7,815,911

Louis Hersh (biochemistry), "Insulin degrading enzyme assays for treatment of alzheimer's disease" # 7,807,396

September 2010
Russell Mumper and Michael Jay (formerly pharmaceutical sciences), "pH-Sensitive mucoadhesive film-forming gels and wax-film composites" # 7,803,392

Jurgen Rohr (pharmaceutical sciences), Carsten Fischer (Lexington, Ky.), "Gilvocarcin gene cluster, recombinant production and use thereof" # 7,799,904

August 2010
Vivek M. Rangnekar (radiation medicine), "Identification of a unique core domain of Par-4 sufficient for selective apoptosis induction in cancer cells" # 7,786,275

Darrell Taulbee (Center for Applied Energy Research), "Reducing explosive potential of ammonium nitrate" # 7,785,553

Stephen Testa (biological chemistry) and Michael Bell (formerly pharmaceutical sciences), "Trans-excision-splicing ribozyme and methods of use" # 7,776,835

July 2010
Clair Hicks (animal and food sciences), Peter Crooks (pharmaceutical sciences), "Bioactive peptide-based probes" # 7,759,468

William A. Bailey (agronomy), Terry Thomas and Thomas A. Losty (Swisher International Inc., Jacksonville, Fla.), John Brandon (Hopkinsville, Ky.), "Method for reducing nitrosamines in tobacco" # 7,757,697

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2010 Patents

31 patents were issued to UK in 2010.

June 2010
Deane Louis Falcone (Agriculture), John M. Littleton (Kentucky Tobacco Research and Development Center) received a patent for "Methods for screening for genes and small molecules that activate mammalian receptor proteins." #7,737,327

Philip Landfield (Molecular and Biomedical Pharmacology), Eric Blalock (Molecular and Biomedical Pharmacology), Kuey-Chu Chen (Molecular and Biomedical Pharmacology) and Thomas Foster (Pharmacy Practice and Science) received a patent for "Biomarkers for aging." #7,739,056

Chang-Guo Zhan (Pharmaceutical Science), Fang Zheng (Pharmaceutical Science) and Wenchao Yang (Pharmacy) received a patent for "High activity mutants of butyrylcholinesterase for cocaine hydrolysis." #7,740,840

John M. Stencel (Chemical and Material Engineering) and Tapiwa Zabron Gurupira (Center for Applied Energy Research) received a patent for "Particle separation/purification system, diffuser and related methods." #7,741,574

Hans Peter Spielmann (Biochemisty) and Douglas A. Andres (Biochemisty) recieved a patent for "Antibodies and unnatural substrates of prenylation enzymes for use in detecting and isolating prenylated proteins." #7,745,589

Robert L. Houtz (Horticulture), Lynnette M. A. Dirk (Horticulture) and Mark Alan Williams (Horticulture) received a patent for "Inhibitors of plant peptide deformylase for use as broad-spectrum herbicides and methods for identifying the same." #7,745,693

Chang-Guo Zhan, Hoon Cho and Hsin-Hsiung Tai (pharmaceutical sciences) received a patent for "High-activity mutants of butyrylcholinesterase for cocaine hydrolysis and method of generating the same." #7,731,957

May 2010
Fadi Abu-Farha (Engineering) and Marwan Khraisheh (Engineering) received a patent for "Uniaxially-driven controlled biaxial testing fixture." #7,712,379

Jeffery Moscow (Medicine), Xin Lu (Shanghai, CN) and Craig Jordan (Rochester, NY) received a patent for "Organic cation transporter preferentially expressed in hematopoietic cells and leukemias and uses thereof." #7,723,019

David Nister (Center for Visualization & Virtual Environments) and Henrik Stewenius (Center for Visualization & Virtual Environments) received a patent for "Scalable object recognition using hierarchical quantization with vocabulary tree." #7,725,484

April 2010
Thomas Burke (deceased, formerly Pharmaceutical Sciences) and Daniel Carter (Huntsville, AL) received a patent for "Methods and compositions for optimizing blood and tissue stability of camptothecin and other albumin-binding therapeutic compounds." #7,691,872

Jamey Jacob (formerly Engineering) received a patent for "An actuator including a first and second conductor on a dielectric, wherein application of voltage to the first conductor creates a plasma, thereby modifying a fluid flow in communication with the actuator. Related systems and methods are also provided." #7,703,479

Peter Oeltgen (Medicine) and Meera Govindaswami (Dentistry) received a patent for "Compositions and methods useful for treating circulatory and hypovolemic shock." #7,705,119

March 2010
Peter Crooks (Pharmaceutical Sciences) and Craig Jordan (Pharmaceutical Sciences) received a patent for "Use of parthenolide derivatives as antileukemic and cytotoxic agents." #7,678,904

February 2010
Sylvia Daunert (Chemistry), Michael Poon (New York, NY), Urvee Desai (San Francisco, CA), Sapna Deo (Chemistry) received a patent for "Method and kit for determination of prostacyclin in plasma." #7,659,078

January 2010
Kyung Bo Kim (Pharmaceutical Sciences) and Yik Khuan Ho (Pharmaceutical Sciences) received a patent for "Epoxyketone-based immunoproteasome inhibitors." #7,642,369

Philip Landfield, inventor, (Molecular and Biomedical Pharmacology) and co-inventor Olivier Thibault (Molecular and Biomedical Pharmacology) received a patent for "Neural network model for instruments that store and retrieve sequential information." #7,643,354

Jordan Craig, inventor, (Pharmaceutical Sciences) received a patent for "Methods to impair hematologic cancer progenitor cells and compounds related thereto." #7,651,678

December 2009
Bruce Webb, inventor, (Agriculture) and co-inventor Jeremy Kroemer (Agriculture) received a patent for "Vectors and methods for enhanced cell longevity and protein expression." #7,629,160

Sylvia Daunert, inventor, (Chemistry) and co-inventors Sapna Kamlakar Deo (Chemistry), Jason Douglas Ehrick (Lexington, KY), Tyler William Browning (Lexington, KY) and Leonidas Bachas (Chemistry) received a patent for "Stimuli-responsive hydrogel microdomes integrated with genetically engineered proteins for high-throughput screening of pharmaceuticals." #7,625,951

November 2009
Bruce Hinds, inventor, (Engineering) received a patent for "Aligned Nanotubule membranes." #7,611,628

Vedanth Srinivasan, inventor, (Farmington Hills, MI) and co-inventors Abraham Salazar (Engineering), Kozo Saito (Engineering), Richard Alloo (Engineering), Masahito Sakakibara (Okazaki, Japan) received a patent for "Devices and methods for atomizing fluids." #7,617,993

Said Ghabrial, inventor, (Agriculture) and co-inventors Chunquan Zhanag (Ames, IA) and Hongcang Gu (Chestnut Hill, MA) received a patent for "Viral vectors useful in soybean and methods of use." #7,618,815

October 2009
Dayong Gao, inventor, (Engineering) and co-inventors XiangDong Cui (Lexington, KY) and Gary Van Zant (Medicine) received a patent for "Methods and devices for cryopreservation of biological cells and tissues." #7,604,930

Susheng Gan, inventor, (Agriculture) and co-inventor Mingtang Xie (Burnaby, CA) received a patent for "Genetic insulator for preventing influence by another gene promoter." #7,605,300

September 2009
Kimberly Anderson, inventor, (Engineering) and co-inventors Kimberly May (Union, N.J.) and Leonidas Bachas (Chemistry) received a patent for "Methods for cancer detection." #7,595,149

Ambati Jayakrishna, inventor (Medicine) received a patent for "Methods and animal model for analyzing age-related macular degeneration." #7,595,430

Avindra Nath, inventor, (Ellicott City, MD) and co-inventors Russell Mumper (formerly UK), Jerold Woodward (Medicine), Zhengrong Cui (formerly UK) received a patent for "Compositions comprising human immunodeficiency virus Tat absorbed to the surface of anionic nanoparticles." #7,588,764

July 2009
Robert Vallance, inventor, (South Riding, VA) and co-inventors Bruce Walcott (Engineering), James Lumpp (Engineering), Aravind Balasubramanian (Engineering) and Osamah Rawashdeh (Engineering) received a patent for "Linear actuator using shape memory wire with controller." #7,555,900

Robert Lodder, inventor, (Pharmacy) received a patent for "Method and system for situ spectroscopic evaluation of an object." #7,557,923

Daniel Wermeling, inventor, (Pharmacy) and co-inventors Ryan Vallance (Engineering), Aravin d Balasubramanian (Engineering), Bruce Walcott (Engineering), John Main (Engineering) and James Lumpp (Engineering) received a patent for "Programmable multi-dose intranasal drug delivery device." #7,559,321

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2009 Patents

21 patents were issued to UK in 2009.

June 2009
Deane Falcone, inventor, (Agriculture) and co-inventor John Littleton (Agriculture) received a patent for "Methods to identify plant metabolites." #7,547,520

Jayakrishna Ambati, inventor, (Medicine) received a patent for "VEGF-A as an inhibitor of angiogenesis and methods of using same." #7,553,496

May 2009
George Wagner, inventor, (Agriculture) and co-inventor Ryan Shepherd (Berkeley, CA) received a patent for "Utility of phylloplanins as antibiotics, selective fungicides and for enhancing microbial resistance in crop plants." #7,528,232

Myron Jacobson, inventor (formerly UK) and co-inventors Elaine Jacobson (formerly UK), Jean-Christophe Ame (Obernai, France) and Winston Lin (formerly UK) received a patent for "Gene encoding several poly (ADP-ribose) glycohydrolase (PARG) enzymes, the proteins and fragments thereof, and antibodies immunoreactive therewith." #7,538,194

April 2009
Daniel Howe (Agriculture) received a patent for "Nucleic acids encoding Sarcocystis neurona antigen and uses thereof." #7,524,946

Nancy Webb, inventor, (Medicine) and co-inventor Frederick DeBeer (Medicine) received a patent for "Compositions and methods for detecting and treating atherosclerosis." #7,521,198

Malaya Chatterjee, inventor, (Medicine) and co-inventors Kenneth Foon and Sunil Chatterjee (Medicine) received a patent for "Monoclonal antibody 1A7 and use for the treatment of melanoma and small cell carcinoma." #7,517,967

David Hildebrand, inventor, (Agriculture) and co-inventor Hirotada Fukushige (Agriculture) received a patent for "Recombinant watermelon (Citrullus lanatus) hydroperoxide lyase and uses thereof." #7,517,679

March 2009
David Jacques, inventor, (Engineering) and co-inventor Rodney Andrews (Engineering) received a patent for "Continuous production of aligned carbon nanotubes." #7,504,078

George Wagner, inventor, (Agriculture) and co-inventor Ryan Sheperd (Berkeley, CA) received a patent for "Method of utilizing the tobacco phylloplanin promoter for expression of nucleic acids as gene products directed to aerial surfaces of plants." #7,501,557

December 2008
Joe Chappell, inventor, (Agriculture) and co-inventor Brian Greenhagen (Agriculture) received a patent for "Sesquiterpene synthase gene and protein." #7,442,785

November 2008
Robert L. Houtz, inventor, (Agriculture) and co-inventors David W. Rodgers (Biochemistry), Lynette Dirk (Agriculture), and Mark A. Williams (Agriculture) received a patent for "The crystallization and structure of a plant peptide deformylase." #7,445,923

Mahendra Kumar Sunkara, inventor, (Louisville, Ky.) and co-inventors Shashank Sharma (Mountain View, Cali.) Uschi M. Graham (Geology) received a patent for "Formation of metal oxide nanowire networks (nanowebs) of low-melting metals." #7,445,671

October 2008
Chang-Guo Zhan, inventor, (Pharmaceutical Sciences) and co-inventors Hoon Cho (Pharmaceutical Sciences) and Hsin-Hsiung Tai (Pharmaceutical Sciences) received a patent for "High-activity mutants of butyrylcholinesterase for cocaine hydrolysis and method of generating the same." #7,438,904

Laurence G. Hassebrook, inventor, (Engineering) and co-inventors Daniel L. Lau (Engineering) and Chun Guan (Engineering) received a patent for "System and technique for retrieving depth information about a surface by projecting a composite image of modulated light patterns." #7,440,590

September 2008
David Atwood, inventor, (Chemistry) received a patent for "Use of boron compounds to precipitate uranium from water." #7,419,604

Robert Houtz, inventor, (Horitculture) and co-inventors Lynnette M. A. Dirk (Horticulture) and Mark Alan Williams (Horticulture) received a patent for "Inhibitors of plant peptide deformylase for use as broad-spectrum herbicides and methods for identifying the same." #7,419,815

Jurgen Rohr, inventor, (Pharmaceutical Sciences) and co-inventors Lily Remsing (Pharmaceutical Sciences), Mohammad Nur-e-Alam, Jose A. Salas (Universidad de Oviedo), Carmen Mendez (Universidad de Oviedo), Alfredo Brana and Ana Gonzalez received a patent for "Derivaties of mithramycin and methods of making and uses thereof." #7,423,008

Elaine Jacobson, inventor, (formerly UK) and co-inventors Myron K. Jacobson (formerly UK) received a patent for "Method for enhancing protective cellular responses to genotoxic stress in skin." #7,425,319

July 2008
Malaya Chatterjee, inventor, (Medicine) and co-inventors Kenneth A. Foon and Sunil K. Chatterjee (Medicine) received a patent for "Murine monoclonal anti-idiotype antibody 11D10 and methods of use thereof." #7,399,849

Joseph Chappell, inventor, (Agriculture) and co-inventor Lyle F. Ralston (Chesterfield, Mo.) received a patent for "Cytochrome P450s and uses thereof." #7,405,671

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2008 Patents

14 patents were issued to UK in 2008.

July 2008
Joseph Chappell, inventor, (Agriculture) and co-inventor Lyle F. Ralston (Chesterfield, Mo.) received a patent for "Cytochrome P450s and uses thereof." #7,405,671

June 2008
John Anthony, inventor, (Chemistry) and co-inventors Marcia Payne (Chemistry), Susan Odom (Chemistry) and Richard Parking (Chemistry) received a patent for "Novel silylethynylated heteroacenes and electronic devices made with these compounds are disclosed." #7,385,221

Rodney Guttmann, inventor, (Physiology) received a patent for "5-mer peptides that can inhibit calpain I and calpain II are disclosed. The peptide sequence is as follows: Leu or Ala)-(Xaa)-(Asp or Glu)-(Xaa)-(Leu or Met), where Xaa can be any amino acid." #7,385,027

May 2008
Peter Crooks, inventor, (Pharmaceutical Sciences) and co-inventors Linda Dwoskin (Pharmaceutical Sciences), Marlon Jones (Compton, CA), Dennis Keith Miller (Columbia, MO), Davin Seth Norholm (Atlanta, GA), Guangrong Zheng (Pharmaceutical Sciences) and Sairam Krishamurthy (Engineering) received a patent for "2,6-distributed piperidines and piperazine compounds." #7,368,443

April 2008
David Hildebrand, inventor, (Agriculture) and co-inventor Tomoko Hatanaka (Hyogo, JP) received a patent for "Recombinant Stokensia epoxygenase gene." #7,364,901

March 2008
Sylvia Daunert, inventor, (Chemistry) and co-inventors Sapna Kamlakar Deo (Chemistry), Emre Dikici (Chemistry) and Laura Rowe (Chemistry) received a patent for "aequorin and obelin mutants with differing wavelengths and bioluminescence." #7,345,160

Rolf Joseph Craven, inventor, (Pharmacology) received a patent for "Hpr6 mutants and uses therof." #7,342,100

February 2008
Peter Oeltgen, inventor, (Pathology) and co-inventors Paul D. Bishop (Fall City, WA), Craig J. McClain (Medicine) and Shirish Barve (Pathology) received a patent for "method for treating a viral infection related to a chemical toxin relate4d hepatic injury with deltorphin D." #7,335,642

Subodh M. Lele, inventor, (Pathology) and co-inventors Manjiri S. Lele (Pathology) and Nada H. Khattar (Oncology) received a patent for "primers and probe to identify mycobacterium tuberculosis complex." #7,332,597

January 2008
Kenneth Calver, inventor, (Computer Science) and co-inventor James N. Griffioen (Computer Science) received a patent for "System and process for providing auxillary information for a packet-switched network of shared nodes using dedicated associative store." #7,317,729

December 2007
Peter Crooks, inventor, (Pharmaceutical Sciences) and co-inventors Craig T. Jordon (Rochester, NY) and Xiaochen Wei (Pharmaceutical Sciences) received a patent for "use of parthenolide derivates as antileukemic and cytotoxic agents." #7,312,242

November 2007
Malaya Chatterjee, inventor, (Microbiology) and co-inventors Kenneth Foon (Fremont, CA) and Sunil K. Chatterjee (Pharmaceutical Sciences) received a patent for "methods of delaying development of CEA-associated tumors using anti-idiotype." #7,300,651

October 2007
Darrell Taulbee, inventor, (Engineering) received a patent for "synthetic fuel and methods of producing synthetic fuel." #7,282,072

August 2007
Grace Jones, inventor, (Biology) and co-inventor Davy Jones (Toxicology), received a patent for "mutants and assay system to identify USP/RXR ligands." #7,259,254
Daniel Howe, inventor, (Veterinary Science) received a patent for "nucleic acids encoding Sarcocystis neurona antigen and uses thereof." #7,256,282

July 2007
Robert Lodder, inventor, (Pharmaceutical Sciences) and co-inventor John Carberry (Talbott, TN) received a patent for "optical monitoring system with molecular filters." #7,251,032

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2007 Patents

24 patents were issued to UK in 2007

June 2007
Bruce Jackson Hinds, III (Chemical and Materials Engineering) and Audra Lynn Stinchcomb (Pharmaceutical Sciences) received a patent for "Delivery system for a composition." #7,229,556

Peter A. Crooks (Pharmaceutical Sciences), Aimee Karis Bence (Indianapolis, IN), and David Robert Worthern (Lexington, KY) received a patent for "Compounds of use in the treatment of epilepsy, seizure, and electroconvulsive disorders." #7,226,949

May 2007
Peter A. Crooks (Pharmaceutical Sciences), Tadeusz Cynkowski (Pharmacy), Grazyna Cynkowska (Pharmacy), Hong Guo (Belmont, MA), and Paul Ashton (Watertown, MA) received a patent for "Permeable, water soluble, non-irritating prodrugs of chemotherapeutic agents with oxaalkanoic acids." #7,214,710

Stephen M. Testa (Biological Chemistry) and Michael A. Bell (Center for Pharmaceutical Science & Technology) received a patent for "Trans-excision-splicing ribozyme and methods of use." #7,211,661

April 2007
Krishnamurty Muralidhar (Decision Science and Information Systems) and Rathindra Sarathy (Stillwater, OK) received a patent for "Data shuffling procedure for masking data." #7,200,757

Fuhua Cheng (Computer Science) received a patent for "Subdivision surface-based geometric modeling system." #7,200,532

March 2007
Joseph Chappell (Plant and Soil Sciences) and Kyoungwhan Back (Kwangju, KR) received a patent for "Plant cells and plants expressing chimeric isoprenoid synthases." #7,186,891

February 2007
Christopher L. Schardl (Plant Pathology), Heather H. Wilkinson (College Station, TX), and Martin J. Spiering (Plant Pathology) received a patent for "Loline alkaloid gene clusters of the fungal endophyte neotyphodium uncinatum." #7,183,098

January 2007
David Allan Atwood (Chemistry) received a patent for "Catalytic cleavage of phosphate ester bonds by boron chelates." #7,166,591

David N. Jacques (Center for Applied Energy Research) and Rodney J. Andrews (Center for Applied Energy Research) received a patent for "Process for the continuous production of aligned carbon nanotubes." #7,160,531

December 2006
David Hildebrand (Plant and Soil Sciences) and Hirotada Fukushige (Plant and Soil Sciences) received a patent for "Recombinant watermelon (Citrullus lanatus) hydroperoxide lyase and uses thereof." #7,153,680

Russell John Mumper (Pharmaceutical Sciences) and Michael Jay (Pharmaceutical Sciences) received a patent for "Microemulsions as precursors to solid nanoparticles." #7,153,525

William L. Boatright (Animal and Food Sciences) received a patent for "Modified soy products and methods for reducing odor and improving flavor of soy products." #7,147,878

November 2006
Christopher O. Jaynes (Computer Science), Stephen B. Webb (Lexington, KY), and Robert M. Steele (Lexington, KY) received a patent for "Dynamic shadow removal from front projection displays." #7,133,083

October 2006
Kozo Saito (Mechanical Engineering), Mohammed I. Hassan Ali (Mechanical Engineering), Akira Numasato (Toyota, JP), Mohammed A. Omar (Lexington, KY), Masahito Sakakibara (Okazaki, JP), Toshikazu Suzuki (Aichi, JP), and (Hebron, KY) received a patent for "Systems and methods for inspecting coatings." #7,129,492

Christopher O. Jaynes (Computer Science) and Robert M. Steele (Lexington, KY) received a patent for "Monitoring and correction of geometric distortion in projected displays." #7,119,833

September 2006
David A. Atwood (Chemistry) received a patent for "Cleavage of phosphate ester bonds by use of novel group 13 chelate compounds." #7,105,703

August 2006
Christopher O. Jaynes (Computer Science) and Divya T. Ramakrishnan (Madras, India) received a patent for "Super-resolution overlay in multi-projector displays." #7,097,311

Fred A. Payne (Biosystems and Agricultural Engineering) received a patent for "System and method for sensing a characteristic of a fluid and related apparatus." #7,092,084

Peter A. Crooks (Pharmaceutical Sciences), Linda Dwoskin (Pharmaceutical Sciences), Rui Xu (Longmont, CO), and Joshua T. Ayers (Chadds Ford, PA) received a patent for "Chain-modified pyridino-N substituted nicotine compounds for use in the treatment of CNS pathologies." #7,091,357

Malaya Chatterjee (Microbiology), Heinz Kohler (Microbiology and Immunology), Sunil K. Chatterjee (Pharmaceutical Sciences), and Kenneth A. Foon (Hematology-Oncology) received a patent for "Murine monoclonal anti-idiotype antibody 3H1 sequences for human carcinoembryonic antigen." #7,090,842

John M. Stencel (Chemical and Materials Engineering) and Tapiwa Zabron Gurupira (Center for Applied Energy Research) received a patent for "Particle separation/purification system, diffuser and related methods." #7,086,535

July 2006
Thomas Tobin (Veterinary Science) received a patent for "Long acting, reversible veterinary sedative and analgesic and method of use." #7,074,834

Marcos Oliveira (Pharmaceutical Sciences) received a patent for "Selective PARP-1 targeting for designing chemo/radio sensitizing agents." #7,072,771

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2006 Patents

20 patents were issued to UK in 2006.

June 2006
Lyndon Scott Stephens (Mechanical Engineering) and Kevin W. Kelly (Baton Rouge, LA) received a patent for "Seal assembly for machinery housing." # 7,066,469

Lori Latus (Markey Cancer Center), Dennis P. Curran (Pittsburgh, PA), Wu Du (San Diego, CA), and Thomas G. Burke [deceased] (Pharmaceutical Sciences) received a patent for "Highly lipophilic camptothecin intermediates and prodrugs and methods of preparation thereof." #7,064,206

Thomas G. Burke [deceased] (Pharmaceutical Sciences), Dennis P. Curran (Pittsburgh, PA), and Wu Du (San Diego, CA) received a patent for "Camptothecin intermediates and prodrugs and methods of preparation thereof." #7,064,202

Peter R. Oeltgen (Pathology), Paul D. Bishop (Fall City, WA), Mark S. Kindy (Nutritional Sciences), and Juan A. Sanchez (Waltham, MA) received a patent for "Protection against ischemia and reperfusion injury." #7,060,792

Daniel K. Howe (Veterinary Science) received a patent for "Nucleic acids encoding Sarcocystis neurona antigen and uses thereof." #7,056,733

May 2006
Indu Bhushan Maiti (KTRDC) and Somnath Bhattacharyya (Barraekpore, India) received a patent for "Methods and composition for expressing multiple genes in plants by alternate splicing of a polycistronic message." #7,052,905

April 2006
Kenneth B. AinHematology-Oncology) and Gopalakrishnan Venkataraman (Endocrinology and Molecular Medicine) received a patent for "Iodine uptake restoration in thyroid cancer." #7,029,879

March 2006
Nader F. Mir (Electrical and Computer Engineering) received a patent for "Packet-switching network with symmetrical topology and method of routing packets." #7,012,895

W. S. Winston Ho (Chemical and Materials Engineering) received a patent for "CO.sub.2-selective membranes containing amino groups." #7,011,694

January 2006
Surjit Randhava (Unitel Technologies, Inc.), W. S. Winston Ho (Chemical and Materials Engineering), Richard L. Kao (Northbrook, IL), and Elias H. Camara (Clarendon Hills, IL) received a patent for "Dynamic sulfur tolerant process and system with inline acid gas-selective removal for generating hydrogen for fuel cells." #6,984,372

December 2005
Arnold J. Stromberg (Statistics) received a patent for "Nonparametric control chart for the range." #6,980,875

Kozo Saito (Mechanical Engineering), Forman A. Williams (La Jolla, CA), Alvin S. Gordon (La Jolla, CA), and Liming Yuan (Mechanical Engineering) received a patent for "Synthesis of multi-wall carbon nanotubes using unseeded hydrocarbon diffusion flames." #6,979,433

November 2005
Peter R. Oeltgen (Pathology) and Mark S. Kindy (Nutritional Sciences) received a patent for "Seventeen amino acid peptide (Peptide P) for treating ischemia and reperfusion injury." #6,967,192

Alexandre N. Terentiev (formerly UK) received a patent for "Pumping or mixing system using a levitating magnetic element." #6,965,288

September 2005
Malaya Chatterjee (Microbiology), Kenneth A. Foon Hematology-Oncology) and Sunil K. Chatterjee (Pharmaceutical Sciences) received a patent for "Murine monoclonal anti-idiotype antibody 11D10 and methods of use thereof." #6,949,244

Daniel P. Wermeling (Pharmacy Practice and Science),Ryan Vallance (Mechanical Engineering), Aravind Balasubramaniam (Lexington, KY), Bruce Lanier Walcott (Electrical Engineering), John Alan Main (Mechanical Engineering), and James E. Lumpp, Jr. (Electrical and Computer Engineering) received a patent for "Programmable multi-dose intranasal drug delivery device." #6,948,492

Linda P. Dwoskin (Pharmaceutical Sciences), Peter A. Crooks (Pharmaceutical Sciences) and Marlon D. Jones (Chemistry) received a patent for "Cis-2,6-disubstituted piperidines for the treatment of psychostimulant abuse and withdrawal, eating disorders, and central nervous system diseases and pathologies." #6,943,177

August 2005
Indu B. Maiti (KTRDC) and Nrisingha Dey (KTRDC) received a patent for "Composition and methods of using the Mirabilis mosaic caulimovirus sub-genomic transcript (Sgt) promoter for plant genetic engineering." #6,930,182

Elaine L. Jacobson (formerly UK), Myron K. Jacobson (Tucson, AZ), Jaber G. Qasem (Tucson, AZ), Hyuntae Kim (Tucson, AZ), and Moonsun Kim (Tucson, AZ) received a patent for "Methods and compositions useful in enhancing oxygen delivery to cells." #6,924,299

July 2005
Robert Ryan Vallance (Mechanical Engineering), Bruce L. Walcott (Electrical Engineering), James E. Lumpp (Electrical and Computer Engineering), Sumanth Chikkamaranahalli (Alexandria, VA), Osamah A. Rawashdeh (Electrical Engineering), and Eric Wolsing (Shoals, IN) received a patent for "System and device for characterizing shape memory alloy wires." #6,916,115

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