UK Home Academics Athletics UK's Chandler Medical Center Research Site Index Search UK

Publications

A non-canonical E-box within the MyoD core enhancer is necessary for circadian expression in skeletal muscle

Xiping Zhang, Samir P. Patel, John J. McCarthy, Alexander G. Rabchevsky, David J. Goldhamer and Karyn A. Esser Click to download

Effective fiber hypertrophy in satellite cell-depleted skeletal muscle

John J. McCarthy, Jyothi Mula, Mitsunori Miyazaki, Rod Erfani, Kelcye Garrison, Amreen B. Farooqui, Ratchakrit Srikuea, Benjamin A. Lawson, Barry Grimes, Charles Keller, Gary Van Zant, Kenneth S. Campbell, Karyn A. Esser, Esther E. Dupont-Versteegden and Charlotte A. Peterson Click to download

Early activation of mTORC1 in response to mechanical overload is independent of PI3K/Akt signaling

Miyazaki M, McCarthy JJ, Fedele MJ, Esser KA. Early activation of mTORC1 in response to mechanical overload is independent of PI3K/Akt signaling. J Physiol. 2011 Feb 7. [Epub ahead of print] PubMed PMID: 21300751Click to download

CLOCK and BMAL1 regulate MyoD and are necessary for maintenance of skeletal muscle phenotype and function

Andrews JL, Zhang X, McCarthy JJ, McDearmon EL, Hornberger TA, Russell B, Campbell KS, Arbogast S, Reid MB, Walker JR, Hogenesch JB, Takahashi JS, Esser KA. CLOCK and BMAL1 regulate MyoD and are necessary for maintenance of skeletal muscle phenotype and function. Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19090-5. Epub 2010 Oct [...]

Aging and MicroRNA Expression in Human Skeletal Muscle: A Microarray and Bioinformatics Analysis

Drummond MJ, McCarthy JJ, Sinha M, Spratt HM, Volpi E, Esser KA, Rasmussen BB. Aging and MicroRNA Expression in Human Skeletal Muscle: A Microarray and Bioinformatics Analysis. Physiol Genomics. 2010 Sep 28. [Epub ahead of print] PubMed PMID: 20876843.Click to download

Comments on Point:Counterpoint: IGF is/is not the major physiological regulator of muscle mass. IGF-1 is not key for adult skeletal muscle hypertrophy

Esser KA, McCarthy JJ, Miyazaki M. Comments on Point:Counterpoint: IGF is/is not the major physiological regulator of muscle mass. IGF-1 is not key for adult skeletal muscle hypertrophy. J Appl Physiol. 2010 Jun;108(6):1830. PubMed PMID: 20527705.Click to download

Comments on Point:Counterpoint: IGF is/is not the major physiological regulator of muscle mass. IGF-1 is not key for adult skeletal muscle hypertrophy

Esser KA, McCarthy JJ, Miyazaki M. Comments on Point:Counterpoint: IGF is/is not the major physiological regulator of muscle mass. IGF-1 is not key for adult skeletal muscle hypertrophy. J Appl Physiol. 2010 Jun;108(6):1830. PubMed PMID: 20527705.Click to download

Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1/TSC2 in C2C12 myotubes

Miyazaki M, McCarthy JJ, Esser KA. Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1/TSC2 in C2C12 myotubes. FEBS J. 2010 May;277(9):2180-91. PubMed PMID: 20412061; PubMed Central PMCID: PMC2892984.Click to download

Anabolic and catabolic pathways regulating skeletal muscle mass

Curr Opin Clin Nutr Metab Care. 2010 May;13(3):230-5. Anabolic and catabolic pathways regulating skeletal muscle mass. McCarthy JJ, Esser KA. Center for Muscle Biology, Department of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky, USA. PMCID: PMC2877703 [Available on 2011/5/1] PMID: 20154608Click to download

The role of clock genes in cardiometabolic disease.

J Appl Physiol. 2009 Oct;107(4):1316-7. Epub 2009 Aug 27. The role of clock genes in cardiometabolic disease. Esser KA, Young ME. PMID: 19713427Click to download

Working around the clock: circadian rhythms and skeletal muscle.

Zhang X, Dube TJ, Esser KA.  Working around the Clock: Circadian rhythms and skeletal muscle.  J. Appl. Physiol.  Aug 20 Epub ahead of print  PMID: 19696362Click to download

Evidence of MyomiR network regulation of beta-myosin heavy chain gene expression during skeletal muscle atrophy.

McCarthy, J.J., K.A. Esser, C.A. Peterson and EE Dupont-Versteegden.  Evidence of MyomiR network regulation of β-myosin heavy chain gene expression during skeletal muscle atrophy, Phys. Genomics, Aug 18. Epub ahead of print: PMID: 19690046Click to download

Physical activity reduces prostate carcinogenesis in a transgenic model

Esser, KA, C. Harpole, A. Diamond, G. Prins. Physical Activity Reduces Prostate Carcinogenesis in a Transgenic Model.  The Prostate. 69(13):1372-7, 2009. PMID: 19489028Click to download

FoxO1 induces apoptosis in skeletal myotubes in a DNA-binding-dependent manner

McLoughlin, T.J., S.M. Smith, H. Wang, T.G. Unterman and K.A.Esser.  FoxO1 induces apoptosis in myotubes in a DNA binding dependent manner. Am.J.Physiol: Cell, Jun 24. Epub, PMID: 19553561Click to download

Regulation of mTOR signaling in skeletal muscle hypertrophy

Esser K. Regulation of mTOR signaling in skeletal muscle hypertrophy. J Musculoskelet Neuronal Interact. 2008 Oct-Dec;8(4):338-9. PubMed PMID: 19147966.Click to download

REDD2 is enriched in skeletal muscle and inhibits mTOR signaling in response to leucine and stretch

Miyazaki M, Esser KA. REDD2 is enriched in skeletal muscle and inhibits mTOR signaling in response to leucine and stretch. Am J Physiol Cell Physiol. 2009 Mar;296(3):C583-92. Epub 2009 Jan 7. PubMed PMID: 19129461; PubMed Central PMCID: PMC2660267.Click to download

Cellular mechanisms regulating protein synthesis and skeletal muscle hypertrophy in animals

Miyazaki M, Esser KA. Cellular mechanisms regulating protein synthesis and skeletal muscle hypertrophy in animals. J Appl Physiol. 2009 Apr;106(4):1367-73. Epub 2008 Nov 26. PubMed PMID: 19036895.Click to download

Aging differentially affects human skeletal muscle microRNA expression at rest and after an anabolic stimulus of resistance exercise and essential amino acids

Drummond MJ, McCarthy JJ, Fry CS, Esser KA, Rasmussen BB. Aging differentially affects human skeletal muscle microRNA expression at rest and after an anabolic stimulus of resistance exercise and essential amino acids. Am J Physiol Endocrinol Metab. 2008 Dec;295(6):E1333-40. Epub 2008 Sep 30. PubMed PMID:18827171; PubMed Central PMCID: PMC2603551.Click to download

Expression of growth-related genes in young and older human skeletal muscle following an acute stimulation of protein synthesis

Drummond MJ, Miyazaki M, Dreyer HC, Pennings B, Dhanani S, Volpi E, Esser KA, Rasmussen BB. Expression of growth-related genes in young and older human skeletal muscle following an acute stimulation of protein synthesis. J Appl Physiol. 2009 Apr;106(4):1403-11. Epub 2008 Sep 11. PubMed PMID: 18787087.Click to download

Counterpoint: Satellite cell addition is not obligatory for skeletal muscle hypertrophy

McCarthy JJ, Esser KA. Counterpoint: Satellite cell addition is not obligatory for skeletal muscle hypertrophy. J Appl Physiol. 2007 Sep;103(3):1100-2; discussion 1102-3. PubMed PMID: 17724306.Click to download