RSS Feed for Molecular and Biomedical Pharmacology
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- Dept. Seminar: Dr. Binhua P. Zhou
posted on November 25, 2009 03:06:16 pm
The Department of Molecular and Biomedical Pharmacology on Thursday, December 3, 2009 will host a seminar to be given by Binhua P. Zhou, M.D., Ph.D., Associate Professor, Markey Cancer Center and Dept. of Molecular and Cellular Biochemistry, University of KY Medical Center. His seminar is entitled: Regulation of EMT In Breast Cancer Metastasis. This seminar will be at 3:00 p.m. in room MN-263 UKMC. - Congratualtions to Jennifer Furman
posted on November 20, 2009 12:12:09 pm
Congratualtions to Ms. Jennifer Furman (Mentor: Dr. Chris Norris) on her first place poster presentation award at the Science Symposium sponsored by Sanders Brown Center on Aging. - Dept. Seminar: Dr. James R. Moyer, Jr
posted on November 09, 2009 04:20:44 pm
On Thursday, November 12 the Department of Molecular and Biomedical Pharmacology will host a seminar to be given by Dr. James R. Moyer, Jr. from the University of Wisconsin-Milwaukee, Department of Psychology. Dr. Moyer's seminar is entitled: Neurobiological Mechanisms of Aging and Cognitive Flexibility. This seminar will be at 3:00 p.m. in room MN-263 UKMC - Congratualtions to Luke Searcy and Lindsay Calderon
posted on October 26, 2009 02:53:28 pm
CONGRATULATIONS to Luke Searcy and Lindsay Calderon for winning first and second place, respectively, at the Gill Heart Cardiovascular Research Day Poster presentation last week! - Alzheimer's Research Forum Article Features the work of The Norris Laboratory (off-campus link)
posted on October 26, 2009 02:52:15 pm
On October 18th, the Alzheimer's Research Forum posted an article entitled "The Skinny on NFATs?Mediators of Ab Toxicity?" The article featured recent work conducted in the lab of Dr. Chris Norris, which showed that cognitive decline in Alzheimer's disease is associated with elevated calcineurin/NFAT signaling in the hippocampus (Mohmmad Abdul et al., 2009, J Neurosci 29:12957?12969). The work was a collaborative effort with the Alzheimer's Disease Center at UK, as well as the labs of Drs. Harry Levine and Paul Murphy of the Sanders-Brown Center on Aging. Dr. Hafiz Mohmmad Abdul, of the Norris lab, spearheaded the study, and former and current pharmacology graduate students, Michelle Sama and Jennifer Furman, also made important contributions. - Dept. Seminar: Dr. John P. O'Bryan
posted on October 21, 2009 01:09:29 pm
On Thursday, October 29th the Department of Molecular and Biomedical Pharmacology will host a seminar to be given by John P. O'Bryan, Ph.D., Assistant Professor, Dept. of Pharmacology at the University of Illinois at Chicago, College of Medicine, Chicago, IL. Dr. O'Bryan's seminar is entitled: "Intersectin Pathways in Cell Biology". This seminar will be at 3:00 p.m. in room MN-263 UKMC. - Markey Research Seminar: Dr. Michael Kilgore
posted on October 19, 2009 03:19:00 pm
Dr. Michael Kilgore is giving a Markey Research Seminar at noon on Friday, October 23 in Room MN-363 of the Medical Science Building. His lecture title is: Targeting the endogenous expression and transactivation of PPARγ as a therapeutic strategy in the treatment of breast cancer. - Markey Research Seminar: Dr. Hollie Swanson (pdf)
posted on October 15, 2009 03:53:20 pm
Dr. Hollie Swanson is giving a Markey Research Seminar at noon on Friday, October 16 in Room MN-263 of the Medical Science Building. The title of her seminar is The Aryl Hydrocarbon Receptor: A Target for Novel Cancer Therapeutics? - Dept. Seminar: Dr. Michal J. Toborek
posted on October 13, 2009 10:51:48 am
On Thursday, October 22, 2009 the Department of Molecular and Biomedical Pharmacology will host a seminar to be given by Michal J. Toborek, M.D., Ph.D., Director of Research, Department of Neurosurgery, University of Kentucky, College of Medicine. Dr. Toborek's seminar is entitled: Repairing The Barrier: Protection Of The Blood Brain Barrier Against HIV-1 Trafficking Into The Brain. This seminar will be at 3:00 p.m. in room MN-263 UKMC. - Please Welcome Our Newest Faculty Member Dr. Xiuwei Yang to the Pharmacology Department
posted on September 24, 2009 11:37:37 am
Dr. Yang comes from the Dana-Farber Cancer Institute and Harvard Medical School. His research focuses on the biology and the microenvironment of cancer cells. He is joined by Dr. Xinyu Deng who obtained his PH.D. at Peking Union Medical University. - Thanks to our Student Representatives
posted on September 09, 2009 02:49:02 pm
We appreciate the efforts of our previous Student Representatives (Marian Novak and Jillian Vanover). We thank them for their service, and welcome our new Student Representatives Heather Buechel and Jenny Furman. - Please welcome IBS rotation students
posted on August 25, 2009 01:06:45 pm
Please welcome Ryan Griggs, an IBS student rotating in Dr. Thibault's lab. - Please Welcome Our Newest Graduate Students
posted on July 22, 2009 10:40:08 am
Please welcome our newest graduate students: Woodrow Friend (Mentor: Dr. Rina Plattner), and Abdel Salous (Mentor: Dr. Andrew Morris). - Pharmacology Orientation Workshop 2009
posted on July 15, 2009 12:20:54 pm
Pharmacology Orientation Workshop for IBS Students will be held on August 11th, 2009. - Ms. Lindsay Calderon Awarded AHA Predoctoral Fellowship
posted on July 15, 2009 12:18:29 pm
Congratulations to Lindsay Calderon for being awarded an American Heart Association predoctoral fellowship. - Grad. Student Seminar: Mr. Marian Novak aand Mr. Jonathan Sims
posted on May 27, 2009 11:28:26 pm
The Department of Molecular and Biomedical Pharmacology will host a seminar to be given by graduate students, Mr. Marian Novak aand Mr. Jonathan Sims on Thursday, May 28th. There talks are entitled: Mr. Marian Novak: NM23-H1 Suppresses Progression to the Metastatic Phenotype Through Its 3'-5' Exonuclease Activity. Faculty Advisor: Dr. David M. Kaetzel Mr. Jonathan Sims: Ab1 Kinase Inhibition Sensitizes Triple-Negative Breast Cancer Cells to Chemotherapeutic Agents. Faculty Advisor: Dr. Rina Plattner This seminar will be at 3:00 p.m in room MN-263 UKMC. - Collaborative work between Dr. Landfield and Dr. Kadish highlighted in Journal of Neuroscience (off-campus link)
posted on May 20, 2009 04:38:14 pm
Dr. Inga Kadish at the University of Alabama, in collaboration with Dr. Philip Landfield's research group here at UK, has recently published an article examining transcriptional changes in hippocampus over the life span of rats (at 3 months- young adult, 6, 9, 12, and 23 months). At each age point, animal cognition was tested using maze learning, and results were correlated with gene expression microarray data from the hippocampus. Microarrays are capable of measuring the expression of thousands of genes simultaneously, and allowed the authors to look at groups of genes related to different processes. Before cognitive decline began, they saw brain metabolism genes apparently shift away from sugar-type fuels, and towards alternative fatty acid fuels. This seemed to cause a problem with cholesterol management, that began to build over later ages and parallels cognitive failure. These results indicate that as cholesterol levels rise in the brain, cognition declines, but that this a downstream consequence of an earlier change in brain metabolism. This work was featured as a "This Week in the Journal" article in the Journal of Neuroscience. Reference: Kadish I, Thibault O, Blalock EM, Chen KC, Gant JC, Porter NM, Landfield PW (2009) Hippocampal and cognitive aging across the lifespan: a bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment. J Neurosci 29:1805-1816. Url: http://www.jneurosci.org/cgi/content/full/29/6/1805 - Dr. Lawrence Brewer and colleagues highlighted in the Journal of Neuroscience (off-campus link)
posted on May 20, 2009 04:41:30 pm
Dr. Lawrence Brewer and colleagues (Brewer et al., 2009) recently published a paper studying estrogen's effects on the aging brain. It was highlighted as a "This Week in the Journal" feature in the Journal of Neuroscience. The authors used a unique approach (the "zipper" slice) to expose and analyze some of the most age-vulnerable neurons in the brain- CA1 pyramidal cells of the hippocampus (important for learning and memory). The authors showed, for the first time, that electrical activity of individual calcium channel molecules in this region not only increases with age in female animals, but is partially reversed by estradiol. Thus, estrogen's reported benefits for brain health and cognition may be related to their ability to preserve normal calcium activity in these neurons. Reference: Brewer LD, Dowling AL, Curran-Rauhut MA, Landfield PW, Porter NM, Blalock EM (2009) Estradiol reverses a calcium-related biomarker of brain aging in female rats. J Neurosci 29:6058-6067. Url: http://www.jneurosci.org/cgi/content/full/29/19/6058 - Grad. Student Seminar: Ms. Ikhlas Ahmed and Ms. Natalie Wallis
posted on May 20, 2009 10:05:48 am
On Thursday, May 21st the Department of Molecular and Biomedical Pharmacology will host a seminar given by graduate students, Ms. Ikhlas Ahmed and Ms. Natalie Wallis. The talks are entitled: Ms. Ikhlas Ahmed: The Role of Pgrm1 In Turmor Proliferation Faculty Advisor: Dr. Rolf Craven Ms. Natalie Wallis: Uncovering a Role of PPAR? in Early Stages of Breast Cancer Progression Faculty Advisor: Dr. Michael Kilgore This seminar will be at 3:00 p.m. in room MN-263 UKMC. - Grad. Student Seminar: Ms. Yekaterina Zaytseva
posted on May 13, 2009 01:19:56 pm
On Thursday, May 14th the Department of Molecular and Biomedical Pharmacology will host a seminar to be given by graduate student, Ms. Yekaterina Zaytseva. Ms. Zaytseva's talk is entitled: Tageting Endogenous PPARγ Signaling as a Potential Approach for Breast Cancer Therapy. Her faculty advisor is Dr. Michael W. Kilgore. This seminar will be at 3:00 p.m. in room MN-263 UKMC.