The Neural Systems Lab is part of UK's Center for Biomedical Engineering started in November 2009. Research at the lab focuses on the modeling and diagnosis of brain state for applications in epilepsy therapy, sleep monitoring, and neural interfaces.
Projects
Modeling sleep-seizure interactions in epilepsy;Dynamic programming of neural interfaces and neurotherapy; and
Characterization of seizures and epileptogenesis following brain trauma.
Funding
Towards a Behavioral Index of Seizure Susceptibility, NINDS R03, 2009-12, PI: Sunderam (University of Kentucky) Neonatal Hypoxia-Ischemia Induced Seizures: Development of Seizure Detection Algorithms, NINDS R03, 2011-13, PI: Vannucci (Cornell-Weill, NY)Selected Publications
(In press) Cuaycong M, Engel M, Weinstein SL, Perlman JM, SALMON E, SUNDERAM S, Vannucci SJ. A novel approach to the study of hypoxia-ischemia induced clinical and subclinical seizures in the neonatal rat. Dev Neurosci, 2011.
SUNDERAM S, Talathi SS, Lyubushin A, Sornette D, Osorio I. Challenges for emerging neurostimulation-based therapies for real-time seizure control. Epilepsy and Behavior, 22(1):118-25, 2011 (invited).
SUNDERAM S. 2011. How to detect and quantify epileptic seizures. In Epilepsy: The intersection of neurosciences, biology, mathematics, physics and engineering, ed. I. Osorio, H. P. Zaveri, M. G. Frei, and S. Arthurs. CRC Press. Osorio I, Manly B, SUNDERAM S. Toward a quantitative multivariate analysis of the efficacy of antiseizure therapies. Epilepsy and Behavior, 18(4):335-343, 2010.
SUNDERAM S, Gluckman BJ, Reato D, Bikson M. Toward rational design of electrical stimulation strategies for epilepsy control. Review. Epilepsy and Behavior, 2010 Jan;17(1):6-22. Epub 2009 Nov 17.
SUNDERAM S, Chernyy N, Peixoto N, Mason JP, Weinstein SL, Schiff SJ, Gluckman BJ. Seizure entrainment with polarizing low frequency electric fields in a chronic animal epilepsy model. J Neural Eng, 6(4):046009, 2009.