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Current Studies and Grants

Blood Flow Restriction Training (BFRT)

BFRT applies a cuff to either the upper (arm) or lower (leg) limb to partially occlude arterial and venous blood flow to muscle.  Partial occlusion of blood flow, is believed to result in metabolites staying in the muscle longer and creating  an environment which promotes adaptation of muscle with minimal strain.  Therefore, individuals are able to train at a lower resistance (20-30% 1RM compared to 70-80% 1RM) and receive the same training benefits as if they were training under high resistance.  BFRT can provide an alternative method for individuals with a range of conditions where resistance training using high loads is contraindicated or not well tolerated.

Research performed at the BioMotion Lab:

  • Healthy individuals
  • ACL management pre-operative and post-operative to understand mechanisms of action (NIH funded)
  • ACL management long-term

Myostatin (MSTN)

The primary aim of the study is to evaluate the time course of the expression of myostatin following an ACL injury and reconstruction on muscle quality. Prior to reconstruction surgery individuals take a Biodex Strength Assessment. Individuals are monitored for 22-26 weeks following surgery through muscle biopsies and blood samples. 

  • Myostatin is a protein that acts to inhibit myogenesis, the formation of muscular tissue. 

Knee Injury Clinical Outcomes Registry (KICOR)

The Biomotion Laboratory is collaborating with the University of Kentucky Orthopedic Department to quantify how individuals progress back to activity after a knee injury. Individuals after anterior cruciate injury are recruited from this registry for additional testing in the "Physical and Psychological Influences on Movement Tendencies and Return to Sports Rates the First Year After Anterior Cruciate Ligament (ACL) Reconstruction" study which is an aggregate of two doctoral students' dissertations.