The final exam will cover Chapters 1–11 in Klein. The following guidelines are not meant to be complete or comprehensive lists of the information you are expected to know.
You are expected to have command of all the material covered on the first, second, and third exams.
You should be able to draw the product of the following reactions, correctly predicting both the regiochemistry and the stereochemistry.
You should be able to draw mechanisms for the reactions of an alkene with:
You should be able to explain the regiochemistry and stereochemistry of any of the reactions above by reference to the reactive intermediates.
You should be able to identify reactions that proceed by a free radical mechanism, and you should be able to correctly draw chain mechanisms for those reactions.
Given a target compound, and using one or more of the reactions above, you should be able to design its synthesis from starting materials with given characteristics. (Look for retrons and do disconnections or functional group interchanges.)
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This page was last updated May 2, 2016.