Title | Forum on aging and skeletal health: summary of the proceedings of an ASBMR workshop. |
Publication Type | Journal Article |
Year of Publication | 2011 |
Authors | Khosla S, Bellido TM, Drezner MK, Gordon CM, Harris TB, Kiel DP, Kream BE, LeBoff MS, Lian JB, Peterson CA, Rosen CJ, Williams JP, Winer KK, Sherman SS |
Journal | J Bone Miner Res |
Volume | 26 |
Issue | 11 |
Pagination | 2565-78 |
Date Published | 2011 Nov |
ISSN | 1523-4681 |
Keywords | Aging, Biomedical Research, Bone and Bones, Bone Resorption, Cellular Senescence, Fractures, Bone, Genetic Predisposition to Disease, Health, Humans, Minerals, Motor Activity, Societies, Scientific |
Abstract | With the aging of the population, the scope of the problem of age-related bone loss and osteoporosis will continue to increase. As such, it is critical to obtain a better understanding of the factors determining the acquisition and loss of bone mass from childhood to senescence. While there have been significant advances in recent years in our understanding of both the basic biology of aging and a clinical definition of age-related frailty, few of these concepts in aging research have been evaluated adequately for their relevance and application to skeletal aging or fracture prevention. The March 2011 Forum on Aging and Skeletal Health, sponsored by the NIH and ASBMR, sought to bring together leaders in aging and bone research to enhance communications among diverse fields of study so as to accelerate the pace of scientific advances needed to reduce the burden of osteoporotic fractures. This report summarizes the major concepts presented at that meeting and in each area identifies key questions to help set the agenda for future research in skeletal aging. |
DOI | 10.1002/jbmr.488 |
Alternate Journal | J. Bone Miner. Res. |
PubMed ID | 21915901 |
PubMed Central ID | PMC3625440 |
Grant List | U13AG037272 / AG / NIA NIH HHS / United States R37 DE012528 / DE / NIDCR NIH HHS / United States UL1 RR025011 / RR / NCRR NIH HHS / United States U13 AG037272 / AG / NIA NIH HHS / United States R01 AR027032 / AR / NIAMS NIH HHS / United States |